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Prophase
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=== Formation of the mitotic spindle === [[Microtubule]]s involved in the [[interphase]] scaffolding break down as the replicated [[centrosome]]s separate.<ref name=":2" /> The movement of [[centrosome]]s to opposite poles is accompanied in [[Cell (biology)|animal cells]] by the organization of individual radial [[microtubule]] arrays (asters) by each centriole.<ref name=":4" /> Interpolar [[microtubule]]s from both [[centrosome]]s interact, joining the sets of [[microtubule]]s and forming the basic structure of the [[Spindle apparatus|mitotic spindle]].<ref name=":4" /> Plant cells do not have centrosomes and the [[chromosome]]s can [[Nucleation|nucleate]] [[microtubule]] assembly into the [[Spindle apparatus|mitotic apparatus]].<ref name=":4" /> In [[plant cell]]s, [[microtubule]]s gather at opposite poles and begin to form the [[spindle apparatus]] at locations called foci.<ref name=":1" /> The [[Spindle apparatus|mitotic spindle]] is of great importance in the process of [[mitosis]] and will eventually segregate the [[sister chromatids]] in [[metaphase]].<ref name=":2" />
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