Editing Rosacea (section)

=== Cathelicidins ===

In 2007, [[Richard Gallo]] and colleagues noticed that patients with rosacea had high levels of  [[cathelicidin]], an [[antimicrobial peptide]],<ref name="pmid17676051">{{cite journal |author1 = Kenshi Yamasaki |author2 = Anna Di Nardo |author3 = Antonella Bardan |author4 = Masamoto Murakami |author5 = Takaaki Ohtake |author6 = Alvin Coda |author7 = Robert A Dorschner |author8 = Chrystelle Bonnart |author9 = Pascal Descargues |author10 = Alain Hovnanian |author11 = Vera B Morhenn |author12 = Richard L Gallo |title = Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea |journal = [[Nature Medicine]] |volume = 13 |issue = 8 |pages = 975–80 |date = August 2007 |pmid = 17676051 |doi = 10.1038/nm1616 |s2cid = 23470611 }}</ref> and elevated levels of [[stratum corneum]] tryptic [[enzyme]]s ([[KLK5|SCTEs]]). [[Antibiotic]]s have been used in the past to treat rosacea, but they may only work because they inhibit some SCTEs.<ref name="pmid17676051" />