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Stabilizing selection
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=== Humans === Stabilizing selection is the most common form of nonlinear selection (non-directional) in humans.<ref>{{cite journal | vauthors = Sanjak JS, Sidorenko J, Robinson MR, Thornton KR, Visscher PM | title = Evidence of directional and stabilizing selection in contemporary humans | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 115 | issue = 1 | pages = 151β156 | date = January 2018 | pmid = 29255044 | doi = 10.1073/pnas.1707227114 | pmc = 5776788 | bibcode = 2018PNAS..115..151S | doi-access = free }}</ref> There are few examples of genes with direct evidence of stabilizing selection in humans. However, most quantitative traits (height, birthweight, schizophrenia) are thought to be under stabilizing selection, due to their polygenicity and the distribution of the phenotypes throughout human populations.<ref>{{cite journal | vauthors = Simons YB, Bullaughey K, Hudson RR, Sella G | title = A population genetic interpretation of GWAS findings for human quantitative traits | journal = PLOS Biology | volume = 16 | issue = 3 | pages = e2002985 | date = 16 March 2018 | pmid = 29547617 | pmc = 5871013 | doi = 10.1371/journal.pbio.2002985 | arxiv = 1704.06707 | doi-access = free }}</ref> * Birth Weight β A classic example of this is human birth weight. Babies of low weight lose heat more quickly and get ill from infectious diseases more easily, whereas babies of large body weight are more difficult to deliver through the pelvis. Infants of a more medium weight survive much more often. For the larger or smaller babies, the baby mortality rate is much higher.<ref>{{cite web | date = 2004 | first = Steven M. | last = Carr | name-list-style = vanc | title = Stabilizing Selection on birthweight in humans | url = https://www.mun.ca/biology/scarr/Stabilizing_Selection_in_Humans.html }}</ref> The bell curve of the human population peaks at a birth weight that the newly born babies exhibit the minimum death rate.
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