Editing Stretch marks (section)

== Treatment ==
There are no clearly useful treatments for stretch marks, although there are many different suggestions on how to remove them or lessen their appearance.<ref name=L2014>{{cite journal | vauthors = Liu L, Ma H, Li Y | title = Interventions for the treatment of stretch marks: a systematic review | journal = Cutis | volume = 94 | issue = 2 | pages = 66–72 | date = August 2014 | pmid = 25184641 }}</ref>

Various efforts that have been tried including [[Laser resurfacing|laser treatments]], [[glycolic acid]], and [[microdermabrasion]].<ref>{{cite journal | vauthors = Al-Himdani S, Ud-Din S, Gilmore S, Bayat A | title = Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment | journal = The British Journal of Dermatology | volume = 170 | issue = 3 | pages = 527–547 | date = March 2014 | pmid = 24125059 | doi = 10.1111/bjd.12681 | s2cid = 13416547 }}</ref> [[Tretinoin]] (0.1% w/w), which is a [[retinoid]], has found to be effective on early stretch marks in several studies. [[Hyaluronic acid]] also improves the appearance of stretch marks.<ref name="MysoreLokhande2019">{{cite journal | vauthors = Lokhande AJ, Mysore V | title = Striae Distensae Treatment Review and Update | journal = Indian Dermatology Online Journal | volume = 10 | issue = 4 | pages = 380–395 | year = 2019 | pmid = 31334056 | pmc = 6615396 | doi = 10.4103/idoj.IDOJ_336_18 | doi-access = free }}</ref><ref name="American Academy of Dermatology 2019">{{cite web | title=Stretch marks: Why they appear and how to get rid of them | website=American Academy of Dermatology | date=2019-11-11 | url=https://www.aad.org/public/cosmetic/scars-stretch-marks/stretch-marks-why-appear | access-date=2020-06-16 | archive-date=10 March 2021 | archive-url=https://web.archive.org/web/20210310113347/https://www.aad.org/public/cosmetic/scars-stretch-marks/stretch-marks-why-appear | url-status=live }}</ref> Topical tretinoin is categorized by the [[Food and Drug Administration|United States Food and Drug Administration]] (FDA) as a known [[teratogen]] (causing malformations in fetuses) in animals, without adequate human studies on safety in pregnancy.<ref name=DailyMed-Tretinoin>{{cite web|title=Renova (tretinoin) cream|url=http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ad4cd608-ee26-4467-9957-a95b33101f9a|work=DailyMed|publisher=FDA and National Library of Medicine|access-date=14 July 2013|archive-date=29 October 2013|archive-url=https://web.archive.org/web/20131029193656/http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ad4cd608-ee26-4467-9957-a95b33101f9a|url-status=live}}</ref>

[[Carboxytherapy]] is a known procedure; however, there is a lack of evidence to support how effective it is.<ref>{{cite press release | year=2009 | title=Carboxytherapy And Mesotherapy Unproven | url=http://www.medicalnewstoday.com/releases/159481.php | access-date=21 May 2016 | archive-date=13 May 2019 | archive-url=https://web.archive.org/web/20190513183046/https://www.medicalnewstoday.com/releases/159481.php | url-status=live }}</ref>

Research into a new [[skin grafting]] technique called "microcolumn grafting / micrografting", which uses needles to take autologous full-thickness [[Skin biopsy|skin biopsies]], is also being investigated as a potential treatment for stretch marks.<ref>{{cite journal | vauthors = Horie Y, Notoya S, Matsuda M, Trovato L | title = Use of autologous micrografting in the treatment of stretch marks | journal = Dermatologic Therapy | volume = 33 | issue = 2 | pages = e13217 | date = March 2020 | doi = 10.1111/dth.13217 | pmid = 31899571 | s2cid = 209671919 | url = https://www.researchgate.net/publication/338376116 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Tam J, Wang Y, Vuong LN, Fisher JM, Farinelli WA, Anderson RR | title = Reconstitution of full-thickness skin by microcolumn grafting | journal = Journal of Tissue Engineering and Regenerative Medicine | volume = 11 | issue = 10 | pages = 2796–2805 | date = October 2017 | pmid = 27296503 | pmc = 5697650 | doi = 10.1002/term.2174 }}</ref><ref>{{cite journal | vauthors = Girão L, Pinto P | title = Efficacy and Safety of an Autologous Micrografting Procedure for Management of Striae Distensae in Women | journal = Dermatology and Therapy | volume = 14 | issue = 2 | pages = 469–488 | date = February 2024 | pmid = 38321354 | pmc = 10891005 | doi = 10.1007/s13555-023-01096-7 }}</ref>

[[V-EMF therapy]]<ref>{{Cite journal |last1=Veronese |first1=Sheila |last2=Bacci |first2=Pier Antonio |last3=Garcia-Gimenez |first3=Victor |last4=Canel Micheloud |first4=Casiana Cecilia |last5=Haro García |first5=Norma Laura |last6=Sbarbati |first6=Andrea |date=2024 |title=V-EMF therapy: A new painless and completely non-invasive treatment for striae gravidarum |journal=Journal of Cosmetic Dermatology |language=en |volume=23 |issue=6 |pages=2007–2014 |doi=10.1111/jocd.16220 |pmid=38549181 |issn=1473-2165|doi-access=free }}</ref><ref>{{Cite journal |last1=Scarano |first1=Antonio |last2=Sbarbati |first2=Andrea |last3=Amore |first3=Roberto |last4=Iorio |first4=Eugenio L. |last5=Ferraro |first5=Giuseppe |last6=Lorusso |first6=Felice |last7=Amuso |first7=Domenico |date=2021 |title=A New Treatment for Stretch Marks and Skin Ptosis with Electromagnetic Fields and Negative Pressure: A Clinical and Histological Study |journal=Journal of Cutaneous and Aesthetic Surgery |volume=14 |issue=2 |pages=222–228 |doi=10.4103/JCAS.JCAS_122_20 |doi-access=free |issn=0974-2077 |pmc=8423202 |pmid=34566367}}</ref> / [[Biodermogenesi|Biodermogenesi®]] treatment (Bi-one® LifeTouchTherapy)<ref>{{Cite web |title=Rigenerazione smagliature - Trattamento antismagliature |url=https://www.bi-one.it/en/bi-one/ |access-date=2025-04-12 |website=Bi-One® |language=en-GB}}</ref> uses a device that generates an electromagnetic field & a negative vacuum (suction) to treat striae, scars & cellulite. Research & marketing claims that the stretch marks - even ones over twenty years old - are able to tan closer to normal skin post-treatment, which should indicate a restructuring of the skin layers that enables melanocytes to function more normally.<ref>{{Cite web |date=2022-10-26 |title=The synergy between vacuum and electromagnetic fields in the treatment of striae distensae: retrospective study on 917 patients with clinical and histological case records |url=https://www.bi-one.it/en/the-synergy-between-vacuum-and-electromagnetic-fields-in-the-treatment-of-striae-distensae-retrospective-study-on-917-patients-with-clinical-and-histological-case-records/ |access-date=2025-04-12 |website=Bi-One® |language=en-GB}}</ref><ref>{{Cite web |date=2022-09-27 |title=TREATMENT OF STRETCH MARKS AGED MORE THAN TWENTY YEARS WITH THE SINERGY OF ELECTROMAGNETICAL FIELD AND VACUUM. CLINICAL CASE STUDIES AND SUBSEQUENT FOLLOW-UP |url=https://www.bi-one.it/treatment-of-stretch-marks-aged-more-than-twenty-years-with-the-sinergy-of-electromagnetical-field-and-vacuum-clinical-case-studies-and-subsequent-follow-up/ |access-date=2025-04-12 |website=Rigenerazione cutanea |language=it-IT}}</ref>