Editing Structural genomics (section)

==== ''ab initio''  modeling====
This approach uses protein sequence data and the chemical and physical interactions of the encoded amino acids to predict the 3-D structures of proteins with no homology to solved protein structures. One highly successful method for ''ab initio'' modeling is the [[Rosetta@home|Rosetta]] program, which divides the protein into short segments and arranges short polypeptide chain into a low-energy local conformation.  Rosetta is available for commercial use and for non-commercial use through its public program, Robetta.