Editing Transferase (section)

===EC 2.1: single carbon transferases===
[[Image:ATCase reaction.svg|thumb|Reaction involving aspartate transcarbamylase.]]
EC 2.1 includes enzymes that transfer single-carbon groups. This category consists of transfers of [[methyl]], [[hydroxymethyl]], formyl, carboxy, [[carbamoyl]], and amido groups.<ref>{{cite web|title=EC 2.1.3: Carboxy- and Carbamoyltransferases|url=http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/1/3/|work=School of Biological & Chemical Sciences at Queen Mary, University of London.|publisher=Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB)|access-date=25 November 2013}}</ref> Carbamoyltransferases, as an example, transfer a carbamoyl group from one molecule to another.<ref>{{cite web|title=carbamoyltransferase|url=http://medical-dictionary.thefreedictionary.com/carbamoyltransferase|work=The Free Dictionary|publisher=Farlex, Inc.|access-date=25 November 2013}}</ref> Carbamoyl groups follow the formula NH<sub>2</sub>CO.<ref>{{cite web|title=carbamoyl group (CHEBI:23004)|url=http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:23004|work=ChEBI: The database and ontology of Chemical Entities of Biological Interest|publisher=European Molecular Biology Laboratory|access-date=25 November 2013}}</ref> In [[Aspartate carbamoyltransferase|ATCase]] such a transfer is written as [[carbamoyl phosphate]] + L-[[aspartate]] <math>\rightarrow</math> L-carbamoyl aspartate + [[phosphate]].<ref>{{cite journal | vauthors = Reichard P, Hanshoff G | title = Aspartate Carbamyl Transferase from ''Escherichia coli'' | journal = Acta Chemica Scandinavica | year = 1956 | pages = 548–566 | url = http://actachemscand.dk/pdf/acta_vol_10_p0548-0566.pdf | doi = 10.3891/acta.chem.scand.10-0548 | volume=10| doi-access = free }}</ref>