Editing Two and a Half Men (section)

== Cast and characters ==
{{Main|List of Two and a Half Men characters}}
[[File:TwoandaHalfMen-Cast.png|thumb|right|270px|The original cast of ''Two and a Half Men'', from left to right: [[Melanie Lynskey]] as Rose, [[Conchata Ferrell]] as Berta, [[Charlie Sheen]] as Charlie Harper, [[Holland Taylor]] as Evelyn Harper, [[Angus T. Jones]] as Jake Harper, [[Jon Cryer]] as Alan Harper and [[Marin Hinkle]] as Judith Harper]]

=== Main ===
* [[Charlie Sheen]] as [[Charlie Harper (Two and a Half Men)|Charlie Harper]] (seasons 1–8), a charismatic [[Hedonism|hedonistic]] [[bachelor]], jingle/children's songwriter, Alan's elder brother, Jake's uncle and Jenny's father. Despite his arrogant and rambunctious demeanor, he does possess a kind heart, though he very rarely shows it. He is written out of the series at the beginning of season nine, after being pushed in front of a train and killed [[offscreen]], due to Charlie Sheen being fired from the show. In the episode "Why We Gave Up Women", Charlie's ghost, portrayed by [[Kathy Bates]], visits Alan and is forced to spend eternity in [[hell]] as a woman with a pair of testicles. He has a daughter named Jenny, whose existence he never disclosed to his family. In season 11, she resurfaces as an adult, but has no idea he had died. The series finale [[retroactive continuity|abandons]] the idea that Charlie is deceased by revealing that Rose faked his death and held him prisoner in a pit for four years. Brainwashed into a violent [[Psychopathy|psychopath]], he escapes and portends his imminent arrival by sending threats to Alan, Evelyn and Walden, as well as generous checks to Jake, Berta, Jenny and his ex-girlfriends, but a helicopter drops a grand piano on him and kills him just before he enters the beach house.
* [[Jon Cryer]] as [[Alan Harper (Two and a Half Men)|Alan Harper]], Charlie's younger brother, a struggling [[chiropractor]], Jake's twice-divorced father, Walden's best friend and Jenny's uncle. Alan is intelligent, a graduate of [[Cal State Long Beach]] but continually stricken with bad luck due to poor choices and mistakes, which are due to a lifetime of suffering from Charlie's abuse and Evelyn's neglect, as well as favoring Charlie over him. Due to a lack in income (partly the result of Charlie's sabotaging Alan's divorce-settlement by jilting Alan's lawyer in the episode "No Sniffing, No Wowing"), Alan is forced to sponge off people throughout his life, but he genuinely cares about others despite this. His poverty ultimately led to the demise of his business. In the 12th and final season, Alan agrees to "marry" Walden for the latter to adopt a child and for months, the two pretend to be a gay couple. In the series' penultimate episode, Walden and Alan end the marriage as Walden had successfully adopted a six-year-old named Louis. Alan finally proposes to Lyndsey and agrees to marry her (as well as move out) in the final episodes. Cryer is the only cast member who appears in all 262 episodes of the series.
* [[Angus T. Jones]] as [[Jake Harper (Two and a Half Men)|Jake Harper]] (seasons 1–10; guest, season 12), the [[slacker]] son of Alan and Judith and older half-brother (or brother, if Alan's paternity claim is to be believed) of Milly and cousin of Jenny. In season one, episode 17 ("Ate the Hamburgers, Wearing the Hats"), his real name is revealed to actually be Jacob. As he grows older, he changes from a rather bright (but gullible), independent child into a dimwitted buffoon (who is nevertheless good at blackmailing Charlie and Alan). He eventually enlists in the U.S. Army working as a chef. At the end of season 10, he announces that he is going to Japan for a year. Despite his absence, he is mentioned often in seasons 11 and 12 and makes an uncredited cameo via archive footage in season 12, as well as returning briefly in person in the series finale.
* [[Ashton Kutcher]] as [[Walden Schmidt]] (seasons 9–12), Alan's best friend, roommate and ephemeral husband. A friendly, hopelessly romantic internet tycoon, he is a billionaire despite being somewhat immature and [[Naivety|naïve]] for most of his life. He purchases the Harper beach house after Charlie's death. During his time in the household, he grows into a responsible adult and forms close friendships with Jake, Herb, Berta, Judith, Evelyn and Jenny. He also serves as a surrogate uncle figure to Jake, in place of Charlie. In season 12, he and Alan adopt a six-year-old boy named Louis.<ref>{{cite news|url=https://tv.yahoo.com/news/tca--ashton-kutcher-to-play-broken-hearted-internet-billionaire-on--two-and-a-half-men-.html?nc|title=TCA: Ashton Kutcher to Play Broken-Hearted Internet Billionaire on 'Two and a Half Men'|publisher=[[Yahoo! TV]]|date=August 3, 2011|access-date=August 4, 2011|archive-date=August 3, 2011|archive-url=https://web.archive.org/web/20110803225856/http://tv.yahoo.com/news/tca--ashton-kutcher-to-play-broken-hearted-internet-billionaire-on--two-and-a-half-men-.html?nc|url-status=live}}</ref>
* [[Holland Taylor]] as [[Evelyn Harper]] (seasons 1–9; recurring, seasons 10–12), Charlie and Alan's vain mother and the grandmother of Jake and Jenny. A high-powered Los Angeles broker/realtor, she is bisexual.
* [[Marin Hinkle]] as [[Judith Melnick|Judith Harper-Melnick]] (seasons 1–9; recurring, seasons 10–12), Alan's selfish, mean-spirited ex-wife and Jake and Milly's mother. She considers Charlie's lifestyle and attitude to be a bad example for Jake and also occasionally has issues with Alan's own parenting practices.
* [[Conchata Ferrell]] as [[Berta (Two and a Half Men)|Berta]] (seasons 2–12; recurring, season 1), the family's outspoken housekeeper and close family friend. She shows great animosity towards Alan and Jake, while she adores Charlie and later, Walden. During the Kutcher years, her role was increased on the show, appearing in more episodes. Season 11 was the first season where she appeared in every episode. The role was originally only intended for a two-episode arc in the first season, in which she would leave as a result of Alan and his son moving in.<ref name="avclub.com"/>
* [[Melanie Lynskey]] as [[Rose (Two and a Half Men)|Rose]] (seasons 1–2; recurring, seasons 3–12), the Harpers' strange neighbor and Charlie's [[Stalking|stalker]] and friend. Initially, Charlie hated Rose and wanted nothing to do with her, but eventually they became friends and he later fell in love with her. In the ninth-season premiere, Rose claimed that Charlie "slipped" in front of a [[Paris Métro]] train after she had caught him cheating on her. She was later seen taking Bridget Schmidt under her wing as an apprentice stalker, but this storyline was eventually aborted. After formally meeting Walden at the local tavern, Rose rushed into a relationship with him and caused her ferrets to attack Walden and Alan when Walden broke up with her. Naturally, she continues to stalk Walden, as well as the Harpers, despite Charlie's apparent death. In the finale, she is revealed to have kept Charlie imprisoned in a pit for four years.
* [[April Bowlby]] as [[Kandi Harper|Kandi]] (season 4; recurring, season 3; guest, seasons 10 and 12),<ref name=BowlbyNote group=note>Prior to appearing as the main character Kandi in [[Two and a Half Men (season 4)|season 4]], April Bowlby had appeared briefly as Kimber in the season-three episode "[[Two and a Half Men (season 3)#ep57|Madame and Her Special Friend]]".</ref> Charlie's dimwitted girlfriend, then later as Alan's girlfriend and second wife and also Judith's best friend (for one episode). In season 10, after Alan rejects her sexual advances, she has a one-night stand with Alan's girlfriend, Lyndsey McElroy.
* [[Jennifer Taylor (actress)|Jennifer Taylor]] as [[Chelsea (Two and a Half Men)|Chelsea]] (season 7; recurring, season 6; guest, seasons 9 and 12),<!-- NOTE BEGINS --><ref name=TaylorNote1 group=note>Prior to appearing as the main character Chelsea from [[Two and a Half Men (season 6)|season 6]] onwards, Taylor had appeared briefly in four previous [[List of Two and a Half Men episodes|episodes]] as three different minor characters: as Suzanne in the series' pilot ([[Two and a Half Men (season 1)|season one]]), as Tina in "Last Chance to See Those Tattoos" ([[Two and a Half Men (season 2)|season two]]) and as Nina in "Our Leather Gear Is in the Guest Room" ([[Two and a Half Men (season 5)|season five]]).</ref><!-- NOTE ENDS --> Charlie's  voluptuous girlfriend for most of season six, she has moved into his house by the end of the season. She then becomes Charlie's fiancée in season seven. They later end the relationship, which deeply hurt Charlie for a while. She is absent throughout season eight, but makes a brief, speaking cameo at Charlie's funeral in season nine. (While credited on-screen among the main cast during the seventh season, CBS press releases billed her as a recurring character.)
* [[Amber Tamblyn]] as Jenny (season 11; recurring, season 12), Charlie's illegitimate daughter who shares many personality traits with her father, including indulging in alcohol and women. She quickly bonds with Alan and Walden, often flaunting her female lovers in front of them. (While credited on-screen among the main cast during the 12th season, CBS press releases bill her as a recurring character.)
* Edan Alexander as [[List of Two and a Half Men characters#Louis|Louis]] (season 12), a six-year-old boy whom Walden adopts.

=== Recurring ===
The following appeared in recurring roles or story arcs spanning multiple episodes:
* [[Jane Lynch]] as the sarcastic Dr. Linda Freeman, originally Jake's child psychologist and later Charlie's regular psychiatrist who later also treats Alan and Walden (seasons 1, 3–9, 11)
* [[Ryan Stiles]] as Herb Melnick, a pediatrician who becomes Judith's second ex-husband (seasons 2, 4–10, 12)
* [[Rebecca McFarland]] as Leanne, Pavlov's bartender (seasons 1–10)
* [[J. D. Walsh (actor)|J. D. Walsh]] as Gordon, a pizza delivery guy who idolizes Charlie's lifestyle (seasons 1–4, 6–8)
* [[Emmanuelle Vaugier]] as Mia, Charlie's ex-fiancée (seasons 3, 5–7 9, and 12)
* [[Robert Wagner]] as Nathan Krunk (alias "Teddy Leopold"), Evelyn's fifth husband, thought to be Courtney's father, but later revealed to be a con artist (seasons 4–5)
* [[Ming-Na Wen]] as the Hon. Linda Harris, superior court judge, adjunct law professor and Charlie's girlfriend (season 5)
* [[Jenny McCarthy]] as Sylvia Fishman (alias "Courtney Leopold"), alleged daughter of Nathan Krunk (alias "Teddy Leopold") (seasons 5, 8–9)
* [[Martin Mull]] as Russell, Charlie's self-medicating pharmacist (seasons 6–10)
* [[Kelly Stables]] as Melissa, Alan's receptionist, who dates both Charlie and Alan (seasons 6–8)
* [[Tinashe Kachingwe]] as Celeste Burnette, Jake's girlfriend whose father strongly disapproves of their relationship (seasons 6–7)
* [[Graham Patrick Martin]] as Eldridge McElroy, Lyndsey's son and Jake's equally dim-witted best friend (seasons 7–9)
* [[Courtney Thorne-Smith]] as Lyndsey McElroy, Alan's on/off love interest from season seven on and his fiancée in season 12. In season 10, she has a one-night stand with Kandi (Alan's ex-wife) (seasons 7–12)
* [[Carl Reiner]] as Marty Pepper, Evelyn's boyfriend and later husband (seasons 7–8, 11)
* [[Judy Greer]] as Bridget, Walden's ex-wife (seasons 9–12); also played Myra Melnick, Herb Melnick's sister and Charlie's one-night fling (season 4)
* [[Mimi Rogers]] as Robin Schmidt, Walden's mother (season 9–12)
* [[Sophie Winkleman]] as Zoey Hyde-Tottingham-Pierce, Walden's love interest following his divorce from Bridget (seasons 9–10, 12)
* Talyan Wright as Ava Pierce, Zoey's seven-year-old daughter (seasons 9–10)
* [[Patton Oswalt]] as Billy Stanhope, Walden's former business partner who dates Bridget (seasons 9–10)
* [[Brooke D'Orsay]] as Kate, Walden's love interest (seasons 10–11); also played Robin, Charlie's sex partner (season 4, episode 16)
* [[Missi Pyle]] as Miss Dolores Pasternak, Jake's teacher (seasons 2, 7, 9 and 12; played by [[Alicia Witt]] in season 6)
* [[Macey Cruthird]] as Megan, Jake's math tutor and later girlfriend (seasons 8–9)
* [[D. B. Sweeney]] as Larry Martin, a good friend of Alan and Walden's, who incidentally, was Lyndsey's boyfriend after Alan (seasons 11–12)
* [[Miley Cyrus]] as Missi, an old family friend of Walden's, who becomes Jake's brief love interest (season 10)
* [[Odette Annable]] as Nicole, brief love interest of Walden and majority owner of a garage-based tech start-up Walden joins (season 11)
* [[Clark Duke]] as Barry Foster, Nicole's business partner who befriends Walden and pretends to be the new "half-man" after Jake moved to Japan (seasons 11–12)
* [[Aly Michalka]] as Brooke, Jenny's girlfriend (season 11)
* [[Kimberly Williams-Paisley]] as Gretchen Martin, Larry Martin's sister, who dates Alan while Larry is with Lyndsey (season 11) (also worked with [[Courtney Thorne-Smith]] on [[American Broadcasting Company|ABC]]'s ''[[According to Jim]]'' as her TV sister)
* [[Maggie Lawson]] as Ms. McMartin, Walden and Alan's social worker for Louis' adoption (season 12)

=== Guest stars ===
Guest stars have included:
* [[Aisha Tyler]] as an adoption lawyer to whom Walden goes when he wants a child (season 12, episode 1)
* [[Alana de la Garza]] as Crystal, Laura Lang's assistant (season 1, episode 21)
* [[Alicia Witt]] as Dolores Pasternak, Jake's teacher who becomes a stripper (season 6)
* [[Allison Janney]] as Beverly, Alan's [[online dating]] partner (season 4)
* [[Amy Hill]] as Mrs. Wiggins, Alan's receptionist after Melissa leaves him (season 7)
* [[Annie Potts]] as Lenore, mother of Judith and Liz (season 7)
* [[Arnold Schwarzenegger]] as Lieutenant Wagner ("Of Course He's Dead", series finale)
* [[Brad Paisley]] as Derek (season 11, episode 22), Gretchen Martin's fiancé, before she broke it off to date Alan
* Brenda Koo as Julie (season 12, episode 7)
* [[Brit Morgan]] as a girl Walden picks up at a bar (season 10, episode 1)
* [[Brooke Shields]] as Danielle, Charlie and Alan's neighbor (season 4)
* [[Camryn Manheim]] as Daisy, Berta's sister (season 2)
* [[Carol Kane]] as Shelly, Melissa's mother (season 6)
* [[Chris O'Donnell]] as Jill/Bill Shrader, Charlie's [[transgender]] ex-girlfriend (season 1, episode 18)
* [[Christian Slater]] as himself (series finale)
* [[Christina Moore]] as Cynthia Sullivan, Judith's best friend (season 5)
* [[Chuck Lorre]] as himself, the program's producer ("[[#ep261/262|Of Course He's Dead]]", series finale)
* [[Cloris Leachman]] as Norma, Charlie and Alan's neighbor, Alan's "sugar momma" and Charlie's former "sugar momma" (season 3)
* [[David Denman]] as Jack (season 12), an old friend of Walden whom he meets at the bar
* [[Deanna Russo]] as Laurel (season 12, episode 7)
* [[Denise Richards]] as Lisa, Charlie's former girlfriend (season 1, episode 10; season 2, episode 9)
* [[Diedrich Bader]] as Dirk, a Denver pawn-shop owner (season 11, episode 21)
* [[Diora Baird]] as Wanda, a girl who chases after Charlie when he is engaged to Chelsea (season 6, episode 16)
* [[Eddie Van Halen]] as himself (season 7, episode 1)
* [[Elvis Costello]] as himself, Charlie's support, whisky and cigar group buddy (season 2, episode 1)
* [[Emilio Estevez]] as Andy, Charlie's long-time friend who dies before him (season 6, episode 11)
* [[Emily Osment]] as Ashley, Jake's girlfriend (season 10, episode 20)
* [[Emily Rose (actress)|Emily Rose]] as Janine (season 6, episode 12)
* [[Enrique Iglesias]] as Fernando, Charlie's carpenter/handyman (season 4, episode 23)
* [[Eric Allan Kramer]] as Bill (season 1)
* [[Erinn Hayes]] as Gretchen, a one-night stand of Alan's (season 8, episode 5)
* Fire Ice as Rapper Cool Dawgie
* [[Frances Fisher]] as Priscilla Honeycutt, Alan's patient (season 7, episode 19)
* [[Gail O'Grady]] as Mandi, mother of Kandi, ex-wife of Andy and brief love interest of Charlie (season 3)
* [[Garry Marshall]] as Garry, one of Marty's friends (season 11, episode 13)
* [[Gary Busey]] as himself, Alan's roommate in a sanitarium (season 9)
* [[Georgia Engel]] as Jean, Lyndsey's mother (season 9, episodes 19–20)
* [[Harry Dean Stanton]] as himself, Charlie's support, whisky and cigar group buddy (season 2, episode 1)
* [[Heather Locklear]] as Laura Lang, Alan's divorce attorney (season 1, episode 21)
* [[Hilary Duff]] as Stacy, a ditzy one-night stand of Walden's (season 10, episode 23)
* [[Ion Overman]] as Vicki, Charlie Waffles' supermarket pickup (season 5, episode 8)
* [[Iqbal Theba]] as Don, a taxi driver who Charlie insults (season 6, episode 13) 
* [[Jack Plotnick]] as Mike (season 5, episode 18)
* [[Jaime Pressly]] as Tammy, Jake's cougar girlfriend (season 10)
* [[James Earl Jones]] as himself (season 6, episode 11)
* [[Jason Alexander]] as Dr. Goodman, Alan's doctor (season 9, episode 23)
* [[Jeff Probst]] as himself, Walden and Alan's love rival (season 11)
* [[Jenna Elfman]] as Frankie (season one, episodes 15 and 16) and as Dharma (season 9, episode 1)
* [[Jeri Ryan]] as Sherri, Charlie's and later Alan's girlfriend (season 2, episodes 5 and 19; season 9, episode 1)
* [[Jessica Collins (actress born 1971)|Jessica Collins]] as Gloria, one of Charlie's one-night stands (season 4, episode 11)
* [[Jodi Lyn O'Keefe]] as Isabella (season 3, episode 6)
* [[John Amos]] as Ed, boyfriend of Chelsea's father Tom (season 7)
* [[John Stamos]] as himself (seasons 9 and 12)
* [[Jon Lovitz]] as Archie Baldwin, Charlie's nemesis to win the advertising jingle award (season 3, episode 17)
* [[Josie Davis]] as Sandy, a girlfriend of Alan's (season 3)
* [[Judd Nelson]] as Chris McElroy, ex-husband of Alan's love interest, Lyndsey, and Eldridge's father (season 8)
* [[Julia Campbell]] as Francine, Jake's teacher (season 3)
* [[Kate Lang Johnson|Kate Miner]] as Nadine Hore (season 11, episode 9)
* [[Katherine LaNasa]] as Lydia, Charlie's oedipal girlfriend and Evelyn's doppelgänger (season 4, episodes 6 and 10)
* [[Kathy Bates]] as "Charlie" in the afterlife (season 9, episode 22)
* [[Katy Mixon]] as Betsy, a married woman whom Charlie purports to marry after his breakup with Chelsea (season 7, episodes 7 and 16)
* [[Ken Jeong]] as a male nurse (season 2, episode 17)
* [[Ken Lerner]] as Dr. Levine (season 6, episode 24)
* [[Kevin Sorbo]] as Andy, father of Kandi, ex-husband of Mandi and brief love interest of Judith (season 3)
* Kris Iyer as Dr. Prajneep (season 1, episode 17; season 4, episode 16; season 5, episode 1)<ref>{{cite web|url=https://www.imdb.com/character/ch0067249/|title=Dr. Prajneep|publisher=IMDb.com|access-date=July 22, 2012|archive-date=July 2, 2013|archive-url=https://web.archive.org/web/20130702021206/http://www.imdb.com/character/ch0067249/|url-status=live}}</ref>
* [[Liz Vassey]] as Michelle (seasons 8–9)
* [[Lucy Lawless]] as Pamela, the ex-wife of the gay ad executive (season 2, episode 18)
* [[Lynda Carter]] as herself (season 11)
* [[Marco Sanchez]] as Hector (season 4, episode 12)
* [[Marilu Henner]] as Linda, Walden's older, more mature love interest (season 10, episode 23)
* [[Martin Sheen]] as Harvey, Rose's father and Evelyn's fling (season 3)
* [[Matthew Marsden]] as Nigel (season 9, episodes 15 and 17), Zoey's ex-husband
* [[Meagen Fay]] as Martha Melini, Chelsea's mother (seasons 6–7)
* [[Megan Fox]] as Prudence, Berta's granddaughter (season 1, episode 12)
* [[Michael Bolton]] as himself (seasons 10 and 12)
* [[Michael Clarke Duncan]] as Jerome Burnette, a retired football player, Charlie and Alan's neighbor and the father of Celeste Burnette (season 6)
* [[Mike Conners]] as Hugo, a brief love interest of Evelyn (season 4, episode 24)
* [[Mila Kunis]] as Vivian, a free-spirit hiker and Walden's love interest (season 11, episode 19)
* [[Morgan Fairchild]] as Donna (Charlie's ego) (season 4, episode 16)
* [[Nadia Bjorlin]] as Jill, a young woman who sleeps with Russell, and Evelyn's one-time lover (season 8)
* [[Noel Fisher]] as Freddie, Prudence's fiancé (season 1, episode 12)
* [[Orson Bean]] as Norman, an old man whose trophy wife had sex with Charlie (season 2, episode 24)
* [[Paget Brewster]] as Jamie Eckleberry, Charlie and Alan's high-school classmate (season 2, episode 12)
* [[Rena Sofer]] as Chrissy, the "mother" of Charlie's "son" (season 6, episode 1)
* [[Richard Kind]] as Artie, Charlie's manager (season 5, episode 8)
* [[Richard Lewis (comedian)|Richard Lewis]] as Stan, Charlie's accountant (season 1, episode 14)
* [[Sam Lerner]] as Andrew, one of Jake's classmates (season 1, episode 8)
* [[Sara Erikson]] as Jennifer, Jake's one-time, older girlfriend (season 9, episode 17)
* [[Sara Rue]] as Naomi, Berta's daughter (season 4)
* [[Scott Bakula]] as Jerry, Ashley's ex-boyfriend (season 10, episode 20)
* [[Sean Penn]] as himself, Charlie's support, whisky and cigar group buddy (season 2, episode 1)
* Skyler Caleb as Serge (season 7, episode 5)
* [[Stacy Keach]] as Tom Melini, Chelsea's father (season 7)
* [[Stephanie Jacobsen]] as Penelope, Charlie's former lover (season 9, episode 2)
* [[Steve Lawrence]] as Steve, one of Marty's friends (season 11, episode 13)
* [[Steven Eckholdt]] as Brad, Alan's lawyer (season 7)
* [[Steven Tyler]] as himself, Charlie and Alan's neighbor and Berta's one-time employer (season 1, episode 4; season 4, episode 2)
* [[Susan Blakely]] as Angie, an author Charlie met at a bookstore (season 5, episodes 18 and 19)
* [[Taylor Cole]] as Melanie Laughlin (season 9)
* [[Teri Hatcher]] as Liz, Judith's sister (season 1, episode 19)
* [[Thomas Gibson]] as Greg (season 9, episode 1)
* [[Tim Conway]] as Tim, one of Marty's friends (season 11, episode 13)
* [[Tinashe|Tinashe Kachingwe]] as Celeste Burnette, Jake's ex-girlfriend (seasons 6–7)
* [[Tony Tripoli]] as Phillip, Evelyn's hairdresser (season 4)
* [[Travis Van Winkle]] as Dylan (season 9, episode 14), a young and rich man who briefly dates Lyndsey
* [[Tricia Helfer]] as Gail, Chelsea's friend (seasons 7 and 9)
* [[Wayne Wilderson]] as Roger, Evelyn's co-worker (season 4)
* [[Will Sasso]] as Andrew, a friend of Charlie's who works in a recording studio (season 7, episode 1)
* [[Willie Garson]] as Dr. Steven Staven, Lyndsey's gynecologist (season 10, episode 14)
* [[Yvette Nicole Brown]] as Mandy (season 1, episode 23)
* [[ZZ Top]] as themselves (season 7, episode 21)

As part of a [[#CSI: Crime Scene Investigation|crossover]] from the writers and executive producer of ''[[CSI: Crime Scene Investigation]]'', [[George Eads]] made a brief [[cameo appearance]] on the [[Fish in a Drawer|May 5, 2008, episode]].<ref>{{cite magazine|last=Rice|first=Lynette|title=George Eads to cameo on 'Two and a Half Men'|url=http://hollywoodinsider.ew.com/2008/04/george-eads-cam.html|magazine=Entertainment Weekly|date=April 12, 2008|access-date=April 24, 2008|archive-url=https://web.archive.org/web/20080426031404/http://hollywoodinsider.ew.com/2008/04/george-eads-cam.html|archive-date=April 26, 2008|url-status=dead}}</ref>

Charlie Sheen's real-life brother [[Emilio Estevez]] has guest-starred as an old friend of Charlie's;<ref>{{cite web|url=https://www.tvguide.com/News/Estevez-Sheen-Men-35396.aspx|title=Two Brothers to Team on ''Two and a Half Men''|work=Tvguide.com|date=November 6, 2008|access-date=August 21, 2011|archive-date=October 29, 2020|archive-url=https://web.archive.org/web/20201029030510/https://www.tvguide.com/news/estevez-sheen-men-35396/|url-status=live}}</ref> his father [[Martin Sheen]] has appeared as Rose's father. Sam Sheen, the real-life daughter of [[Denise Richards]] and Charlie Sheen, appeared as Lisa's daughter on November 22, 2004.<ref>{{IMDb name|id=1775196|name=Sam Sheen}}</ref> [[Mila Kunis]], Ashton Kutcher's fiancée and later wife, appeared on the show as his love interest in season 11.