Editing Valine (section)

=== Degradation ===
Like other branched-chain amino acids, the catabolism of valine starts with the removal of the amino group by [[transamination]], giving [[Alpha-Ketoisovaleric acid|alpha-ketoisovalerate]], an alpha-[[keto acid]], which is converted to [[isobutyryl-CoA]] through [[oxidative decarboxylation]] by the [[Branched-chain alpha-keto acid dehydrogenase complex|branched-chain α-ketoacid dehydrogenase complex]].<ref name=":0">{{Cite book|title=Biochemistry| vauthors = Mathews CK |date=2000|publisher=Benjamin Cummings|others=Van Holde, K. E., Ahern, Kevin G.|isbn=978-0-8053-3066-3 |edition=3rd|location=San Francisco, Calif.|pages=776|oclc=42290721}}</ref> This is further oxidised and rearranged to [[succinyl-CoA]], which can enter the [[citric acid cycle]] and provide direct fuel in muscle tissue.<ref>{{cite web |url=https://www.stanfordchem.com/l-valine.html |title=L-Valine |website=Stanford Chemicals |access-date=Oct 29, 2024}}</ref><ref>{{cite book |last=Kumari |first=Asha |year=2023 |title=Sweet Biochemistry |edition=5th |pages=9–15 |chapter=Chapter 2 - Citric acid cycle |publisher=Academic Press |isbn=9780443153488}}</ref>