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Vocal cord nodule
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== Pathophysiology == Vocal fold nodules often alter the mechanical properties of the vocal folds, which can interfere with their vibratory characteristics.<ref name="Verdolini et al 2014 Vocal Fold Nodules" /><ref name="Colton et al 2006 Nodules" /> Nodules may increase the mass of the vocal folds, especially along the medial edge where they are typically found. This increased mass may result in aperiodic or irregular vibration, the perception of greater pitch and loudness perturbations, and of increased hoarseness.<ref name="Colton et al 2006 Nodules" /> Nodules may also affect the mucosal wave of the vocal folds by changing the configuration of the vocal fold closure pattern. They often cause incomplete closure of the vocal folds, resulting in an hourglass configuration.<ref name="Verdolini et al 2014 Vocal Fold Nodules" /><ref name="pmid14631179" /><ref name="Colton et al 2006 Nodules" /> The incomplete closure allows more air to escape through the vocal folds, which often results in the perception of breathiness.<ref name="Verdolini et al 2014 Vocal Fold Nodules" /><ref name="pmid14631179" /> The degree to which nodules will affect the mucosal wave and vibratory characteristics of the vocal folds depends highly on the size of the nodule.<ref name="Verdolini et al 2014 Vocal Fold Nodules" /><ref name="pmid14631179" /> Smaller nodules may still allow the vocal folds to achieve complete closure.<ref name="Verdolini et al 2014 Vocal Fold Nodules" />
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