Editing Hashimoto's thyroiditis (section)

==== Anti-thyroid antibodies in pregnancy ====
The presence of Thyroid peroxidase antibodies at the outset of pregnancy are associated with a greater risk to the mother of hypothyroidism and thyroid impairment in the first year after [[Childbirth|delivery]].<ref>{{cite journal | vauthors = Caturegli P, De Remigis A, Rose NR | title = Hashimoto thyroiditis: clinical and diagnostic criteria | journal = Autoimmunity Reviews | volume = 13 | issue = 4–5 | pages = 391–397 | date = 2014-04-01 | pmid = 24434360 | doi = 10.1016/j.autrev.2014.01.007 | series = Diagnostic criteria in Autoimmune diseases }}</ref>

The presence of antibodies is also associated with "a 2 to 4-fold increase in the risk of recurrent [[Miscarriage|miscarriages]], and 2 to 3-fold increased risk of [[preterm birth]]", however the reason why is unclear. Thyroid peroxidase antibodies are speculated to indicate other autoimmune processes against the placental-fetal unit.<ref name="Klubo-Gwiezdzinska-2022" />

Levothyroxine treatment in euthyroid women with thyroid autoimmunity does not significantly impact the relative risk of miscarriage and preterm delivery, or outcomes with live birth. "Therefore, no strong recommendations regarding the therapy in such scenarios could be made, but consideration on a case-by-case basis might be implemented."<ref name="Klubo-Gwiezdzinska-2022" />