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African clawed frog
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=== Epigenetic aging=== In ''[[X. laevis]]'', [[epigenetics|epigenetic]] methylation changes in neural-developmental genes associated with aging are analogous to aging related epigenetic changes in mammalian species.<ref name = Zoller2024>{{cite journal |vauthors=Zoller JA, Parasyraki E, Lu AT, Haghani A, Niehrs C, Horvath S |title=DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging |journal=Geroscience |volume=46 |issue=1 |pages=945β960 |date=February 2024 |pmid=37270437 |pmc=10828168 |doi=10.1007/s11357-023-00840-3 }}</ref> This finding suggests that, during their evolutionary divergence, patterns of epigenetic changes in neural-development genes during aging have been conserved between frogs and mammals C.<ref name = Zoller2024/>
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