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Buffer solution
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===Common buffer compounds used in biology=== For effective range see [[#buffer capacity|Buffer capacity]], above. Also see [[Good's buffers]] for the historic design principles and favourable properties of these buffer substances in biochemical applications. {| class="wikitable" |- ! Common name (chemical name) ! Structure ! [[Acid dissociation constant|p''K''<sub>a</sub>]], <br/>25 Β°C ! {{abbr|Temp.|Temperature}} effect, <br/>{{sfrac|dpH|d''T''}} (K<sup>β1</sup>)<ref>{{Cite web |title=Buffer Reference Center |url=http://www.sigmaaldrich.com/life-science/core-bioreagents/biological-buffers/learning-center/buffer-reference-center.html |publisher=Sigma-Aldrich |access-date=2009-04-17 |url-status=live |archive-url=https://web.archive.org/web/20090417003507/http://www.sigmaaldrich.com/life-science/core-bioreagents/biological-buffers/learning-center/buffer-reference-center.html |archive-date=2009-04-17 }}</ref> ! [[Molecular weight|Mol. <br/>weight]] |- | [[TAPS (buffer)|TAPS]], <br/>([tris(hydroxymethyl)methylamino]propanesulfonic acid) | [[file:TAPS.svg|200px]] || 8.43 || β0.018 || 243.3 |- | [[Bicine]], <br/>(2-(bis(2-hydroxyethyl)amino)acetic acid) | [[file:Bicine.png|150px]] || 8.35 || β0.018 || 163.2 |- | [[Tris]], <br/>(tris(hydroxymethyl)aminomethane, or <br/>2-amino-2-(hydroxymethyl)propane-1,3-diol) | [[file:tris.png|100px]] || 8.07{{efn|text=Tris is a base, the p''K''<sub>a</sub> = 8.07 refers to its conjugate acid.}} || β0.028 || 121.14 |- | [[Tricine]], <br/>(N-[tris(hydroxymethyl)methyl]glycine) ||[[file:Tricine.svg|150px]] || 8.05 || β0.021 || 179.2 |- | [[TAPSO (buffer)|TAPSO]], <br/>(3-[N-tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid) ||[[file:TAPSO.svg|200px]] || 7.635 || || 259.3 |- | [[HEPES]], <br/>(4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) | [[file: HEPES.png|200px]] || 7.48 || β0.014 || 238.3 |- | [[TES (buffer)|TES]], <br/><nowiki>(2-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]ethanesulfonic acid)</nowiki> | [[file:TES free acid.svg|200px]] || 7.40 || β0.020 || 229.20 |- | [[MOPS]], <br/>(3-(N-morpholino)propanesulfonic acid) | [[file:Mops is.svg|150px]] || 7.20 || β0.015 || 209.3 |- | [[PIPES]], <br/>(piperazine-N,Nβ²-bis(2-ethanesulfonic acid)) | [[file:PIPES.svg|200px]] || 6.76 || β0.008 || 302.4 |- | [[Cacodylate]], <br/>(dimethylarsenic acid) | [[file:Cacodylic acid.svg|100px]] || 6.27 || || 138.0 |- | [[MES (buffer)|MES]], <br/>(2-(N-morpholino)ethanesulfonic acid) | [[file:MES.svg|150px]] || 6.15 || β0.011 || 195.2 |} {{noteslist}}
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