Editing Calorie restriction (section)

===Life extension===
As of 2021, [[intermittent fasting]] and calorie restriction remain under preliminary research to assess the possible effects on disease burden and increased lifespan during aging, although the relative risks associated with long-term fasting or calorie restriction remain undetermined.<ref name=lee/>

Intermittent fasting refers to periods with intervals during which no food but only clear fluids are ingested – such as a period of daily time-restricted eating with a window of 8 to 12 hours for any caloric intake – and could be combined with overall calorie restriction and variants of the [[Mediterranean diet]] which may contribute to long-term cardiovascular health and longevity.<ref>{{Cite journal |vauthors=O'Keefe JH, Torres-Acosta N, O'Keefe EL, Saeed IM, Lavie CJ, Smith SE, Ros E |date=September 2020 |title=A pesco-Mediterranean diet with intermittent fasting: JACC Review Topic of the Week |journal=Journal of the American College of Cardiology |volume=76 |issue=12 |pages=1484–1493 |doi=10.1016/j.jacc.2020.07.049 |pmid=32943166 |s2cid=221787788 |doi-access=free}}</ref>