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Cell division
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=== Prometaphase === [[Prometaphase]] is the second stage of cell division. This stage begins with the complete breakdown of the nuclear envelope which exposes various structures to the cytoplasm. This breakdown then allows the [[spindle apparatus]] growing from the [[centrosome]] to attach to the [[kinetochore]]s on the sister chromatids. Stable attachment of the spindle apparatus to the kinetochores on the sister chromatids will ensure error-free chromosome segregation during anaphase.<ref>{{cite book |doi=10.1016/B978-0-12-821618-7.30064-5 |chapter=Mitosis in Animal Cells |title=Encyclopedia of Cell Biology |date=2016 |last1=Lian |first1=A.T.Y. |last2=Chircop |first2=M. |pages=298β313 |isbn=978-0-12-821624-8 }}</ref> Prometaphase follows prophase and precedes metaphase.
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