Editing Coliform bacteria (section)

==== Chemiluminescent in-situ hybridization ====
Specific areas of the [[16S rRNA]] in the ''Enterobacteriaceae'' genus are bound by [[oligonucleotide]] probes, which aids in monitoring the quality of drinking water.<ref name=":1" /> Specifically, ''E. coli'' is labelled with a soybean peroxidase-labeled peptide nucleic acid (PNA) probes that bind to a specific sequence in their 16S rRNA. When used in conjunction with a [[Chemiluminescence|chemiluminescent]] substrate, light is produced where each colony of ''E. coli'' is located, indicating that they are present in the sample.<ref>{{cite journal | vauthors = Stender H, Broomer AJ, Oliveira K, Perry-O'Keefe H, Hyldig-Nielsen JJ, Sage A, Coull J | title = Rapid detection, identification, and enumeration of Escherichia coli cells in municipal water by chemiluminescent in situ hybridization | journal = Applied and Environmental Microbiology | volume = 67 | issue = 1 | pages = 142–147 | date = January 2001 | pmid = 11133438 | pmc = 92533 | doi = 10.1128/aem.67.1.142-147.2001 | bibcode = 2001ApEnM..67..142S }}</ref>