Editing Draize test (section)

==Differences between the rabbit eye and the human eyes==

Kirk Wilhelmus, professor in the Department of Ophthalmology at [[Baylor College of Medicine]], conducted a comprehensive review of the Draize eye test in 2001. He also reported that differences in anatomy and biochemistry between the rabbit and human eye indicate that testing substances on rabbits might not predict the effects on humans. However, he noted "that eyes of rabbits are generally more susceptible to irritating substances than the eyes of humans" making them a conservative [[animal model|model]] of the human eye. Wilhelmus concluded "The Draize eye test ... has assuredly prevented harm" to humans, but predicts it will be "supplanted as ''in vitro'' and clinical alternatives emerge for assessing irritancy of the ocular surface".<ref name="Wilhelmus"/>