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Intramuscular injection
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=== Aspiration === Aspirating for blood to rule out injecting into a blood vessel is not recommended by the US [[Centers for Disease Control and Prevention|CDC]], [[Public Health Agency of Canada]], or [[Norwegian Institute of Public Health|Norway Institute of Public Health]], as the injection sites do not contain large blood vessels and aspiration results in greater pain.<ref name="CDCPink">{{cite book|url=https://www.cdc.gov/vaccines/pubs/pinkbook/vac-admin.html|title=The Pinkbook|date=25 September 2019|publisher=[[Centers for Disease Control and Prevention|CDC]]|language=en-us|chapter=Vaccine Administration|quote=Aspiration is not recommended before administering a vaccine.|access-date=12 September 2020|author1=JoEllen Wolicki |author2=Elaine Miller}}</ref><ref>{{cite web|date=2020-12-02|title=Vaccine administration practices: Canadian Immunization Guide|url=https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-1-key-immunization-information/page-8-vaccine-administration-practices.html |access-date=2021-05-25|website=Public Health Agency of Canada |quote=Aspiration before injection of vaccine is not recommended, as there are no large blood vessels at the recommended immunization sites and not aspirating before injection has been demonstrated to reduce pain.}}</ref><ref>{{cite web|title=Praktisk info om vaksinasjon|url=https://www.fhi.no/nettpub/vaksinasjonsveilederen-for-helsepersonell/vaksinasjon/praktisk-vaksinasjon/ |access-date=2021-05-25|website=Folkehelseinstituttet|date=9 April 2008 |language=no|quote=However, it is not recommended to aspirate before intramuscular and subcutaneous vaccine injection provided that the vaccine is placed in the appropriate place … does not involve the risk of injecting intravenously because there are no large blood vessels in these sites. Aspiration can cause the vaccination to be more painful because it takes longer to give the vaccine}}</ref> There is no evidence that aspiration is useful to increase safety of intramuscular injections when injecting in a site other than the dorsogluteal site.<ref name="Nurs2015" /> Aspiration was recommended by the [[Danish Health Authority]] for [[COVID-19 vaccine|COVID-19 vaccines]] for a time to investigate the potential rare risk of blood clotting and bleeding, but it is no longer a recommendation.<ref>{{cite web|date=2021-03-20|title=Covid-19 vacciner skal gives med aspiration før injektion|url=https://dsr.dk/politik-og-nyheder/nyhed/covid-19-vacciner-skal-gives-med-aspiration-foer-injektion|access-date=2021-05-25|website=Politik og nyheder, DSR|language=da|quote=The Danish Health and Medicines Authority's guidelines have long recommended this, and now the Statens Serum Institut is following suit.|archive-date=2021-03-22|archive-url=https://web.archive.org/web/20210322170314/https://dsr.dk/politik-og-nyheder/nyhed/covid-19-vacciner-skal-gives-med-aspiration-foer-injektion|url-status=dead}}</ref><ref>{{cite web|last=name|title=Intramuskulær injektion på børn og voksne|url=https://www.ssi.dk/vaccinationer/injektionsteknik/intramuskulaer-injektion-beorn-og-voksne |access-date=2023-10-04|website=Statens Serum Institut |language=da|quote=It has previously been recommended to aspirate before injection with Covid-19 vaccines in relation to investigation of a possible connection between injection with Vaxzevria® and the occurrence of rare and serious side effects. However, this is no longer a recommendation and Covid-19 vaccines can be injected without prior aspiration.}}</ref>
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