Editing Iron overload (section)

==== Non-classical hereditary hemochromatosis ====

The overwhelming majority of hereditary hemochromatoses are caused by mutations of the HFE gene discovered in 1996, but since then others have been discovered and sometimes are grouped together as "non-classical hereditary hemochromatosis",<ref name="pmid18762941">{{cite journal |last1=Mendes |first1=Ana Isabel |last2=Ferro |first2=Ana |last3=Martins |first3=Rute |last4=Picanço |first4=Isabel |last5=Gomes |first5=Susana |last6=Cerqueira |first6=Rute |last7=Correia |first7=Manuel |last8=Nunes |first8=António Robalo |last9=Esteves |first9=Jorge |title=Non-classical hereditary hemochromatosis in Portugal: novel mutations identified in iron metabolism-related genes |journal=Annals of Hematology |volume=88 |issue=3 |pages=229–34 |year=2008 |pmid=18762941 |doi=10.1007/s00277-008-0572-y |last10=Fleming |first10=Rita |last11=Faustino |first11=Paula|s2cid=23206256 |url=https://hal.archives-ouvertes.fr/hal-00477968/file/PEER_stage2_10.1007%252Fs00277-008-0572-y.pdf }}</ref> "non-HFE related hereditary hemochromatosis",<ref name="isbn0-7817-6040-2">{{cite book |author1=Maddrey, Willis C. |author2=Schiff, Eugene R. |author3=Sorrell, Michael F. |title=Schiff's diseases of the liver |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2007 |pages=1048  |isbn=978-0-7817-6040-9 }}</ref> or "non-HFE hemochromatosis".<ref name="pmid16315138">{{cite journal |last1=Pietrangelo |first1=Antonello |title=Non-HFE Hemochromatosis |journal=Seminars in Liver Disease |volume=25 |issue=4 |pages=450–60 |year=2005 |pmid=16315138 |doi=10.1055/s-2005-923316|s2cid=260320984 }}</ref> They are hemochromatosis [[Juvenile hemochromatosis|type 2]] (2A and 2B), [[Haemochromatosis type 3|type 3]], [[Hemochromatosis type 4|type 4]], type 5<ref>https://rarediseases.info.nih.gov/diseases/13472/hemochromatosis-type-5.</ref>