Editing Lead(II) nitrate (section)

== Safety ==
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{{main|Lead poisoning}}
Lead(II) nitrate is toxic, and ingestion may lead to acute lead poisoning, as is applicable for all soluble lead compounds.<ref name="icsc">{{cite web|title = Lead nitrate, Chemical Safety Card 1000|url = http://www.inchem.org/documents/icsc/icsc/eics1000.htm |publisher = [[International Labour Organization]], International Occupational Safety and Health Information Centre|date=March 1999|access-date = 2008-01-19}}</ref> All [[Inorganic compounds by element#Lead (Plumbum)|inorganic lead compounds]] are classified by the [[International Agency for Research on Cancer]] (IARC) as [[List of IARC Group 2A carcinogens|probably carcinogenic to humans]] (Category&nbsp;2A).<ref name="IARC1">{{cite journal|publisher=[[International Agency for Research on Cancer]] |year=1987 |url=http://monographs.iarc.fr/ENG/Monographs/suppl7/suppl7.pdf |title=Inorganic and Organic Lead Compounds |journal=IARC Monographs on the Evaluation of Carcinogenic Risks to Humans |volume=Suppl. 7 |access-date=2008-01-19 |page=239 |url-status=dead |archive-url=https://web.archive.org/web/20080306134819/http://monographs.iarc.fr/ENG/Monographs/suppl7/suppl7.pdf |archive-date=2008-03-06 }}</ref> They have been linked to [[renal cell carcinoma|renal cancer]] and [[glioma]] in experimental animals and to renal cancer, [[brain tumor|brain cancer]] and [[lung cancer]] in humans, although studies of workers exposed to lead are often complicated by concurrent exposure to [[arsenic]].<ref name="IARC2">{{cite journal|publisher = [[International Agency for Research on Cancer]]|year = 2006|url = http://monographs.iarc.fr/ENG/Monographs/vol87/volume87.pdf|title = Inorganic and Organic Lead Compounds|journal = IARC Monographs on the Evaluation of Carcinogenic Risks to Humans|volume = 87|isbn = 92-832-1287-8|access-date = 2008-01-01|author = World Health Organization, International Agency for Research on Cancer|url-status=dead|archive-url = https://web.archive.org/web/20071021091930/http://monographs.iarc.fr/ENG/Monographs/vol87/volume87.pdf|archive-date = 2007-10-21}}</ref> Lead is known to substitute for [[zinc]] in a number of [[enzyme]]s, including [[porphobilinogen synthase|δ-aminolevulinic acid dehydratase]] (porphobilinogen synthase) in the [[heme|haem]] biosynthetic pathway and [[Nucleotidase|pyrimidine-5′-nucleotidase]], important for the correct metabolism of [[DNA]] and can therefore cause fetal damage.<ref name=mohammed>{{cite journal|last = Mohammed-Brahim|first = B.|author2 = Buchet, J.P. |author3=Lauwerys, R. |title = Erythrocyte pyrimidine 5'-nucleotidase activity in workers exposed to lead, mercury or cadmium|journal = Int Arch Occup Environ Health|year = 1985|volume = 55|issue = 3|pages = 247–52|pmid = 2987134|doi = 10.1007/BF00383757|s2cid = 40092031}}</ref>