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Lethal dose
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==<span id="LDLo"></span>Lowest lethal dose== The lowest lethal dose (LD<sub>Lo</sub>) is the least amount of drug that can produce death in a given animal species under controlled conditions.<ref>[http://www.ccohs.ca/oshanswers/chemicals/ld50.html What is an LD50 and LC50] {{webarchive|url=https://web.archive.org/web/20150626013647/http://www.ccohs.ca/oshanswers/chemicals/ld50.html |date=2015-06-26 }}</ref><ref>{{cite web |date=24 June 2011 |title=Allergan Receives FDA Approval for First-of-Its-Kind, Fully in vitro, Cell-Based Assay for BOTOX® and BOTOX® Cosmetic (onabotulinumtoxinA) |publisher=Allergan Web site |url=http://agn.client.shareholder.com/releasedetail.cfm?ReleaseID=587234 |access-date=2012-08-15 |url-status=dead |archive-url=https://web.archive.org/web/20110626185759/http://agn.client.shareholder.com/releasedetail.cfm?ReleaseID=587234 |archive-date=26 June 2011 }}</ref> The dosage is given per unit of bodyweight (typically stated in [[milligram]]s per [[kilogram]]) of a substance known to have resulted in fatality in a particular species. When quoting an LD<sub>Lo</sub>, the particular species and method of administration (''e.g.'' ingested, inhaled, [[intravenous]]) are typically stated.
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