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Mass spectrum
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===Spectral skewing=== '''Spectral skewing''' is the change in relative intensity of mass spectral peaks due to the changes in concentration of the [[analyte]] in the [[ion source]] as the mass spectrum is scanned. This situation occurs routinely as [[Chromatography|chromatographic]] components [[Elution|elute]] into a continuous ion source.<ref>Watson, J. THrock, Sparkman, O David.Introduction to Mass Spectrometry.John Wiley & Sons, Inc. 4th Edition, 2007. Page:113</ref> Spectral skewing is not observed in [[ion trap]] ([[Quadrupole ion trap|quadrupole]] (this has been seen also in [[Quadrupole mass spectrometer|QMS]]) or magnetic) or [[Time-of-flight mass spectrometry|time-of-flight]] (TOF) [[mass analyzer]]s because potentially all [[ion]]s formed in operational cycle (a snapshot in time) of the instrument are available for detection.
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