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Editing
Myenteric plexus
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===Role in CNS disorders=== Because the ENS is known as the "brain of the gut", due to its similarities with the CNS, researchers have been using colonic biopsies of Parkinson's patients to help better understand and manage [[Parkinson's disease]].<ref>{{cite journal |doi=10.1212/WNL.0b013e31824bd195 |pmid=22371415 |title=Parkinson Disease: The Enteric Nervous System Spills its Guts |journal=Neurology |volume=78 |issue=9 |pages=683; author reply 683 |year=2012 |last1=Shprecher |first1=D. R. |last2=Derkinderen |first2=P. |doi-access= }}</ref> PD patients are known to experience severe constipation due to GI tract dysfunction years before the onset of motor movement complications, which characterises Parkinson's disease.<ref>{{cite journal |doi=10.1371/journal.pone.0012728 |pmid=20856865 |pmc=2939055 |title=Colonic Biopsies to Assess the Neuropathology of Parkinson's Disease and Its Relationship with Symptoms |journal=PLOS ONE |volume=5 |issue=9 |pages=e12728 |year=2010 |last1=Lebouvier |first1=Thibaud |last2=Neunlist |first2=Michel |last3=Bruley Des Varannes |first3=Stanislas |last4=Coron |first4=Emmanuel |last5=Drouard |first5=Anne |last6=n'Guyen |first6=Jean-Michel |last7=Chaumette |first7=Tanguy |last8=Tasselli |first8=Maddalena |last9=Paillusson |first9=Sébastien |last10=Flamand |first10=Mathurin |last11=Galmiche |first11=Jean-Paul |last12=Damier |first12=Philippe |last13=Derkinderen |first13=Pascal |bibcode=2010PLoSO...512728L |doi-access=free }}</ref>
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