Editing Open reading frame (section)

===Investigator===
ORF Investigator<ref>{{cite journal | vauthors = Dhar DV, Kumar MS |title=ORF Investigator: A New ORF finding tool combining Pairwise Global Gene Alignment |journal=Research Journal of Recent Sciences |date=2012 |volume=1 |issue=11 |pages=32–35}}</ref> is a program which not only gives information about the coding and non coding sequences but also can perform pairwise global alignment of different gene/DNA regions sequences. The tool efficiently finds the ORFs for corresponding amino acid sequences and converts them into their single letter amino acid code, and provides their locations in the sequence. The pairwise global alignment between the sequences makes it convenient to detect the different mutations, including [[single nucleotide polymorphism]]. [[Needleman–Wunsch algorithm]]s are used for the gene alignment. The ORF Investigator is written in the portable [[Perl]] [[programming language]], and is therefore available to users of all common operating systems.