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Promethazine
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==History== Promethazine was first synthesized by a group at [[Rhone-Poulenc]] (which later became part of [[Sanofi]]) led by Paul Charpentier in the 1940s.<ref>{{cite journal | vauthors = Ban TA | title = The role of serendipity in drug discovery | journal = Dialogues in Clinical Neuroscience | volume = 8 | issue = 3 | pages = 335β44 | date = 2006 | pmid = 17117615 | pmc = 3181823 | doi = 10.31887/DCNS.2006.8.3/tban }}</ref> The team was seeking to improve on [[diphenhydramine]]; the same line of medical chemistry led to the creation of [[chlorpromazine]].<ref>{{cite web|title=Paul Charpentier, Henri-Marie Laborit, Simone Courvoisier, Jean Delay, and Pierre Deniker|url=https://www.sciencehistory.org/historical-profile/paul-charpentier-henri-marie-laborit-simone-courvoisier-jean-delay-and-pierre|publisher=Science History Institute|access-date=20 March 2018|language=en|date=6 August 2015|archive-date=20 March 2018|archive-url=https://web.archive.org/web/20180320230738/https://www.sciencehistory.org/historical-profile/paul-charpentier-henri-marie-laborit-simone-courvoisier-jean-delay-and-pierre|url-status=dead}}</ref>
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