Editing Propionic acidemia (section)

==History==
In 1957, a male child was born with poor mental development, repeated attacks of acidosis, and high levels of [[ketone]]s and [[glycine]] in the blood. Upon dietary testing, Dr. [[Barton Childs]] discovered that his symptoms worsened when given the amino acids leucine, isoleucine, valine, methionine, and threonine. In 1961, the medical team at [[Johns Hopkins Hospital]] in [[Baltimore]], [[Maryland]] published the case, calling the disorder '''ketotic hyperglycinemia'''. In 1969, using data from the original patient's sister, scientists established that propionic acidemia was a recessive disorder, and that propionic acidemia and [[methylmalonic acidemia]] are caused by deficiencies in the same enzyme pathway.<ref>{{cite web|last=Hsia |first=T. |title=How Ketotic Hyperglycinemia Became Propionic Acidemia| publisher=Paresearch.org |date=2003 |access-date=7 June 2018 |url=http://www.paresearch.org/images/HistoryofPADrHsia.pdf}}</ref>