Editing Pyruvate dehydrogenase complex (section)

=== Dihydrolipoyl dehydrogenase Binding protein (E3BP) ===
An auxiliary protein unique to most eukaryotes is the [[E3 binding protein]] (E3BP), which serves to bind the E3 subunit to the PDC complex. In the case of human E3BP, hydrophobic [[proline]] and [[leucine]] residues in the BP interact with the surface recognition site formed by the binding of two identical E3 monomers.<ref>{{cite journal |last1=Ciszak |first1=E. M. |last2=Makal |first2=A. |last3=Hong |first3=Y. S. |last4=Vettaikkorumakankauv |first4=A. K. |last5=Korotchkina |first5=L. G. |last6=Patel |first6=M. S. |title=How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex |journal=Journal of Biological Chemistry |date=2006 |volume=281 |issue=1 |pages=648–655 |doi=10.1074/jbc.m507850200|pmid=16263718 |s2cid=26797600 |doi-access=free }}</ref>