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Testicle
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====Primary cell types==== Within the seminiferous tubules, the germ cells develop into [[spermatogonia]], [[spermatocyte]]s, [[spermatid]]s and spermatozoa through the process of spermatogenesis. The gametes contain DNA for fertilization of an [[ovum]].<ref>[https://books.google.com/books?id=FoSiGTXn6BUC&q=testes+OR+testis+OR+testicle+OR+testicles Histology, A Text and Atlas] {{Webarchive|url=https://web.archive.org/web/20230629155731/https://books.google.com/books?id=FoSiGTXn6BUC&q=testes+OR+testis+OR+testicle+OR+testicles |date=2023-06-29 }} by Michael H. Ross and Wojciech Pawlina, Lippincott Williams & Wilkins, 5th ed, 2006{{page needed|date=April 2022}}</ref> Sertoli cells{{Snd}}the true epithelium of the seminiferous epithelium, critical for the support of germ cell development into spermatozoa. Sertoli cells secrete [[inhibin]].<ref name="Huhtaniemi">{{Cite book|last=Huhtaniemi|first=Ilpo|title=Encyclopedia of Endocrine Diseases|date=2018|publisher=Academic Press|isbn=978-0-12-812200-6|page=667|url=https://books.google.com/books?id=nVh7DwAAQBAJ&pg=RA1-PA667|access-date=2022-06-02|archive-date=2023-06-29|archive-url=https://web.archive.org/web/20230629155732/https://books.google.com/books?id=nVh7DwAAQBAJ&pg=RA1-PA667|url-status=live}}</ref> [[Peritubular myoid cells]] surround the seminiferous tubules.<ref name="Schlegel">{{Cite book|last1=Schlegel|first1=P.N.|last2=Katzovitz|first2=M.A.|title=Urologic Principles and Practice|chapter=Male Reproductive Physiology|chapter-url=https://books.google.com/books?id=bNHHDwAAQBAJ&pg=PA50|date=2020|publisher=Springer Nature|isbn=978-3-03-028599-9|page=50|access-date=2022-06-02|archive-date=2023-06-29|archive-url=https://web.archive.org/web/20230629155757/https://books.google.com/books?id=bNHHDwAAQBAJ&pg=PA50|url-status=live}}</ref> Between tubules (interstitial cells) exist [[Leydig cells]]<ref name="Bitzer">{{Cite book|last1=Bitzer|first1=Johannes|last2=Mahmood|first2=Tahir A.|title=Handbook of Contraception and Sexual Reproductive Healthcare|date=2022|publisher=Cambridge University Press|isbn=978-1-10-895863-9|page=16|url=https://books.google.com/books?id=WWtYEAAAQBAJ&pg=PA16|access-date=2022-07-05|archive-date=2023-06-29|archive-url=https://web.archive.org/web/20230629155732/https://books.google.com/books?id=WWtYEAAAQBAJ&pg=PA16|url-status=live}}</ref>{{Snd}}cells localized between seminiferous tubules that produce and secrete [[testosterone]] and other [[androgen]]s important for [[puberty]] (including [[secondary sexual characteristics]] like facial hair), [[Human sexual activity|sexual behavior]], and [[libido]]. Sertoli cells support spermatogenesis.<ref name="Miell">{{Cite book|last1=Miell|first1=John|last2=Davies|first2=Zoe|title=Clinical Biochemistry: Metabolic and Clinical Aspects|chapter=Reproductive function in the male|chapter-url=https://books.google.com/books?id=2FkXAwAAQBAJ&pg=PA451|date=2014|publisher=Elsevier Health Sciences|isbn=978-0-70-205478-5|page=451|access-date=2022-07-05|archive-date=2023-06-29|archive-url=https://web.archive.org/web/20230629160234/https://books.google.com/books?id=2FkXAwAAQBAJ&pg=PA451|url-status=live}}</ref> Testosterone controls testicular volume. Immature Leydig cells and interstitial [[macrophage]]s and [[epithelial cells]] are also present.
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