Editing Hashimoto's thyroiditis (section)

==== Hypothyroidism in pregnancy. ====
Women who have low thyroid function that has not been stabilized are at greater risk of complications for both parent and child. Risks to the mother include [[Gestational Hypertension|gestational hypertension]] including [[Pre-eclampsia|preeclampsia]] and [[eclampsia]], [[gestational diabetes]], [[placental abruption]], and [[Postpartum bleeding|postpartum hemorrhage]].<ref name="Klubo-Gwiezdzinska-2022" /> Risks to the infant include miscarriage, preterm delivery, [[low birth weight]], [[Infant respiratory distress syndrome|neonatal respiratory distress]], [[hydrocephalus]], [[hypospadias]], fetal death, infant intensive care unit admission, and [[Developmental disability|neurodevelopmental delays]] (lower child IQ, language delay or [[global developmental delay]]).<ref name="Lepoutre-2012" /><ref name="Gaberšček-2011">{{cite journal | vauthors = Gaberšček S, Zaletel K | title = Thyroid physiology and autoimmunity in pregnancy and after delivery | journal = Expert Review of Clinical Immunology | volume = 7 | issue = 5 | pages = 697–706; quiz 707 | date = September 2011 | pmid = 21895480 | doi = 10.1586/eci.11.42 | doi-access = free }}</ref><ref name="Klubo-Gwiezdzinska-2022" />

Successful pregnancy outcomes are improved when hypothyroidism is treated.<ref name="Gaberšček-2011" /> Levothyroxine treatment may be considered at lower TSH levels in pregnancy than in standard treatment.<ref name="Klubo-Gwiezdzinska-2022" /> Liothyronine does not cross the fetal blood-brain barrier, so liothyronine (T<sub>3</sub>) only or liothyronine + levothyroxine (T<sub>3</sub> + T<sub>4</sub>) therapy is not indicated in pregnancy.<ref name="Klubo-Gwiezdzinska-2022" />

Close cooperation between the [[endocrinologist]] and [[obstetrician]] benefits the woman and the infant.<ref name="Lepoutre-2012" /><ref>{{cite journal | vauthors = Budenhofer BK, Ditsch N, Jeschke U, Gärtner R, Toth B | title = Thyroid (dys-)function in normal and disturbed pregnancy | journal = Archives of Gynecology and Obstetrics | volume = 287 | issue = 1 | pages = 1–7 | date = January 2013 | pmid = 23104052 | doi = 10.1007/s00404-012-2592-z | url = https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/84394 | url-status = live | access-date = 16 January 2022 | s2cid = 24969196 | archive-url = https://web.archive.org/web/20220123170145/https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/84394 | archive-date = 23 January 2022 }}</ref><ref>{{cite journal | vauthors = Balucan FS, Morshed SA, Davies TF | title = Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance | journal = Journal of Thyroid Research | volume = 2013 | pages = 182472 | date = 2013 | pmid = 23691429 | pmc = 3652173 | doi = 10.1155/2013/182472 | doi-access = free }}</ref>