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Hashimoto's thyroiditis
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==== Immune changes during pregnancy ==== Hormonal changes and [[trophoblast]] expression of key [[Immunomodulation|immunomodulatory]] molecules lead to [[immunosuppression]] and fetal tolerance. The main players in regulation of the immune response are [[Tregs]]. Both [[Cell-mediated immunity|cell-mediated]] and [[Humoral immunity|humoral]] immune responses are attenuated, resulting in [[Immune tolerance in pregnancy|immune tolerance]] and suppression of autoimmunity. It has been reported that during pregnancy, levels of thyroid peroxidase and thyroglobulin antibodies decrease.<ref name="Weetman-2010" />
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