Editing Alu element (section)

=== Associated human mutations ===
* The ''ACE'' gene, encoding [[angiotensin-converting enzyme]], has 2 common variants, one with an ''Alu'' insertion (''ACE''-I) and one with the ''Alu'' deleted (''ACE''-D). This variation has been linked to changes in sporting ability: the presence of the ''Alu'' element is associated with better performance in endurance-oriented events (e.g. triathlons), whereas its absence is associated with strength- and power-oriented performance.<ref name=pmid21615186>{{cite journal |doi=10.2165/11588720-000000000-00000 |pmid=21615186 |title=The ACE Gene and Human Performance |journal=Sports Medicine |volume=41 |issue=6 |pages=433–48 |year=2011 |last1=Puthucheary |first1=Zudin |last2=Skipworth |first2=James RA |last3=Rawal |first3=Jai |last4=Loosemore |first4=Mike |last5=Van Someren |first5=Ken |last6=Montgomery |first6=Hugh E |s2cid=42531424 }}</ref>
* The [[opsin]] [[gene duplication]] which [[Evolution of color vision in primates|resulted]] in the re-gaining of [[trichromacy]] in [[Catarrhini|Old World primates]] (including humans) is flanked by an ''Alu'' element,<ref name=pmid10413401>{{cite journal |pmid=10413401 |url=http://genome.cshlp.org/cgi/pmidlookup?view=long&pmid=10413401 |year=1999 |last1=Dulai |first1=K. S |title=The evolution of trichromatic color vision by opsin gene duplication in New World and Old World primates |journal=Genome Research |volume=9 |issue=7 |pages=629–38 |last2=von Dornum |first2=M |last3=Mollon |first3=J. D |last4=Hunt |first4=D. M |doi=10.1101/gr.9.7.629|s2cid = 10637615|doi-access=free }}</ref> implicating the role of ''Alu'' in the evolution of three colour vision.