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Antiarrhythmic agent
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===Class V and others=== Since the development of the original Vaughan Williams classification system, additional agents have been used that do not fit cleanly into categories I through IV. Such agents include: * [[Adenosine]] is used intravenously for terminating [[supraventricular tachycardia]]s.<ref name="pmid7882485">{{cite journal |vauthors=Conti JB, Belardinelli L, Utterback DB, Curtis AB |title=Endogenous adenosine is an antiarrhythmic agent |journal=Circulation |volume=91 |issue=6 |pages=1761β1767 |date=March 1995 |pmid=7882485 |doi=10.1161/01.cir.91.6.1761 }}</ref> * [[Digoxin]] decreases conduction of electrical impulses through the AV node and increases vagal activity via its action on the central nervous system. Via indirect action, it leads to an increase in [[acetylcholine]] production, stimulating M2 receptors on AV node leading to an overall decrease in speed of conduction. * [[Magnesium sulfate]] is an antiarrhythmic drug, but only used against very specific arrhythmias<ref name="pmid10924290">{{cite journal |author=Brugada P |title=Magnesium: an antiarrhythmic drug, but only against very specific arrhythmias |journal=Eur. Heart J. |volume=21 |issue=14 |page=1116 |date=July 2000 |pmid=10924290 |doi=10.1053/euhj.2000.2142 |doi-access=free }}</ref> such as [[torsades de pointes]].<ref name="pmid15466950">{{cite journal |vauthors=Hoshino K, Ogawa K, Hishitani T, Isobe T, Eto Y |title=Optimal administration dosage of magnesium sulfate for torsades de pointes in children with long QT syndrome |journal=J Am Coll Nutr |volume=23 |issue=5 |pages=497Sβ500S |date=October 2004 |pmid=15466950 |doi=10.1080/07315724.2004.10719388 |s2cid=30146333 }}</ref><ref name="pmid16635167">{{cite journal |vauthors=Hoshino K, Ogawa K, Hishitani T, Isobe T, Etoh Y |title=Successful uses of magnesium sulfate for torsades de pointes in children with long QT syndrome |journal=Pediatr Int |volume=48 |issue=2 |pages=112β117 |date=April 2006 |pmid=16635167 |doi=10.1111/j.1442-200X.2006.02177.x |s2cid=24904388 }}</ref>
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