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Axilla
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==Clinical significance== Like other flexion surfaces of large joints ([[groin]], [[popliteal fossa]], [[cubital fossa]] and essentially the anterior part of the [[neck]]), it is an area where blood vessels and nerves pass relatively superficially, and with an increased amount of [[lymph node]]s. ===Lymphogenic spread of breast cancer=== Breast cancer typically spreads via lymphatic vessels to the [[Lymph node|lymph nodes]] found in the axilla.<ref>{{Cite journal |last=Bertozzi |first=Serena |last2=Cedolini |first2=Carla |last3=Londero |first3=Ambrogio P. |last4=Baita |first4=Barbara |last5=Giacomuzzi |first5=Francesco |last6=Capobianco |first6=Decio |last7=Tortelli |first7=Marta |last8=Uzzau |first8=Alessandro |last9=Mariuzzi |first9=Laura |last10=Risaliti |first10=Andrea |date=January 2019 |title=Sentinel lymph node biopsy in patients affected by breast ductal carcinoma in situ with and without microinvasion: Retrospective observational study |url=https://pubmed.ncbi.nlm.nih.gov/30608397/ |journal=Medicine |volume=98 |issue=1 |pages=e13831 |doi=10.1097/MD.0000000000013831 |issn=1536-5964 |pmc=6344146 |pmid=30608397}}</ref> ===Axillary intertrigo=== Excessive [[perspiration]] without adequate air circulation can result in axillary [[intertrigo]]. Intertrigo is an inflammatory [[skin condition]] of skin folds exposed to friction or maceration in the presence of heat and moisture.<ref name="webmd">Selden, Samuel [http://emedicine.medscape.com/article/1087691-overview Intertrigo]. emedicine, WebMD. March 9, 2007. Accessed May 21, 2009.</ref> Intertrigo is worsened by infection, usually fungal ([[Candida (fungus)|Candida]] yeast species), but also bacterial or viral; warm, wet underarms promote those growths. The condition results in rash-like symptoms, [[pustule]]s, or chronic itching or burning in the underarm.<ref name="webmd" /> Intertrigo (in any site) has no racial or sexual predilection.<ref name=webmd/> Axillary intertrigo is common among those who work in hot environments where air circulation is restricted by necessary clothing or safety equipment.<ref>{{cite web |url=https://www.webmd.com/skin-problems-and-treatments/guide/intertrigo-symptoms-causes-treatment-risk_factors_|title=Intertrigo|last=Gardner |first=Stephanie S |date=14 June 2020 |website=WebMD |access-date=June 22, 2021}}</ref>
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