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Blepharitis
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=== Procedures === Cultures of the eyelid margins can be a clear indicator for patients who have recurrent anterior blepharitis with severe inflammation, in addition to patients who are not responding to therapy.<ref name=":0" /> Measurements of tear osmolarity may be beneficial in diagnosing concurrent [[dry eye syndrome]] (DES), which may be responsible for overlapping symptoms and would allow the physician to decipher between conditions and move forward with the most beneficial protocol for the patient. Consequently, the measurement of tear osmolarity has various limitations in differentiating between aqueous deficiencies and evaporative dry eye.<ref name="pmid19668387">{{cite journal | vauthors = Savini G, Prabhawasat P, Kojima T, Grueterich M, Espana E, Goto E | title = The challenge of dry eye diagnosis | journal = Clinical Ophthalmology | volume = 2 | issue = 1 | pages = 31β55 | date = March 2008 | pmid = 19668387 | pmc = 2698717 | doi = 10.2147/opth.s1496 | doi-access = free }}</ref> Microscopic evaluation of [[Epilation|epilated]] eyelashes may reveal mites, which have been evident in cases of chronic [[blepharoconjunctivitis]]. A [[biopsy]] of the eyelid can also determine the exclusion of carcinoma, therapy resistance, or unifocal recurrent [[Chalazion|chalazia]].<ref>{{cite journal | vauthors = Nemoto Y, Arita R, Mizota A, Sasajima Y | title = Differentiation between chalazion and sebaceous carcinoma by noninvasive meibography | journal = Clinical Ophthalmology | volume = 8 | pages = 1869β1875 | date = September 2014 | pmid = 25258508 | pmc = 4172083 | doi = 10.2147/OPTH.S69804 | doi-access = free }}</ref>
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