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Ciliary body
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==Clinical significance== [[Glaucoma]] is a group of ocular disorders characterized by high [[intraocular pressure]]-associated neuropathies.<ref>{{cite journal |doi=10.1111/j.1442-9071.2012.02773.x |url=https://zenodo.org/record/1065544 |pmid=22356435 |title=Definition of glaucoma: Clinical and experimental concepts |journal=Clinical & Experimental Ophthalmology |volume=40 |issue=4 |pages=341β9 |year=2012 |last1=Casson |first1=Robert J |last2=Chidlow |first2=Glyn |last3=Wood |first3=John PM |last4=Crowston |first4=Jonathan G |last5=Goldberg |first5=Ivan |doi-access=free |hdl=2440/73277 |hdl-access=free }}</ref> Intraocular pressure depends on the levels of production and resorption of aqueous humor. Because the ciliary body produces aqueous humor, it is the main target of many medications against [[glaucoma]]. Its inhibition leads to the lowering of aqueous humor production and causes a subsequent drop in the [[intraocular pressure]]. There 3 main types of medication affecting the ciliary body:<ref>{{cite web |title=Glaucoma Medications and Their Side Effects |date=10 January 2024 |publisher=Glaucoma Research Foundation |url=http://www.glaucoma.org/treatment/glaucoma-medications-and-their-side-effects.php}}</ref><ref>{{cite web |title=Medication Guide |publisher=Glaucoma Research Foundation |url=http://www.glaucoma.org/treatment/medication-guide.php}}</ref> *[[Beta blockers]], the second most common treatment method for glaucoma, reduce the production of aqueous humor. They are relatively inexpensive and are available in generic form. [[Timolol]], [[Levobunolol]], and [[Betaxolol]] are common beta blockers prescribed to treat glaucoma. *[[Alpha-adrenergic agonist]]s work by decreasing production of fluid and increasing drainage. [[Brimonidine]] and [[Apraclonidine]] are two commonly prescribes alpha agonists for glaucoma treatment. Alphagan P uses a purite preservative, which is better tolerated by those who have allergic reactions than the older BAK preservative in other eye drops.<ref>{{Cite news|url=https://www.reviewofophthalmology.com/article/the-pros-and-cons-of-preservatives|title=The Pros and Cons of Preservatives|last=Colo.|first=Malik Y. Kahook, MD, Aurora|access-date=2017-03-13}}</ref> Furthermore, less selective alpha agonists such as [[epinephrine]] may decrease the production of aqueous humor through vasoconstriction of the ciliary body (only for open-angle glaucoma).{{citation needed|date=May 2015}} *[[Carbonic anhydrase inhibitors]] also decrease fluid production. They are available as eye drops ([[Trusopt]] and [[Azopt]]) and pills ([[Diamox]] and [[Neptazane]]). This may be helpful if using more than one type of eye medication.{{citation needed|date=May 2015}}
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