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Cyclooxygenase
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=== Effects of COX on the immune system === Inhibition of COX-2 using celecoxib has been shown to reduce the immunosuppressive TGFΞ² expression in hepatocytes attenuating EMT in human hepatocellular carcinoma<ref name="pmid22097969">{{cite journal | vauthors = Ogunwobi OO, Wang T, Zhang L, Liu C | title = Cyclooxygenase-2 and Akt mediate multiple growth-factor-induced epithelial-mesenchymal transition in human hepatocellular carcinoma | journal = Journal of Gastroenterology and Hepatology | volume = 27 | issue = 3 | pages = 566β78 | date = March 2012 | pmid = 22097969 | pmc = 3288221 | doi = 10.1111/j.1440-1746.2011.06980.x }}</ref>
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