Editing Depersonalization (section)

=== Biological ===
Studies have linked dysregulation of the [[immune system]] with depersonalisation.<ref>{{Cite journal |last=Zheng |first=Sisi |last2=Feng |first2=Sitong |last3=Song |first3=Nan |last4=Chen |first4=Guangyao |last5=Jia |first5=Yuan |last6=Zhang |first6=Guofu |last7=Liu |first7=Min |last8=Li |first8=Xue |last9=Ning |first9=Yanzhe |last10=Wang |first10=Dan |last11=Jia |first11=Hongxiao |date=2024-05-27 |title=The role of the immune system in depersonalisation disorder |url=https://www.tandfonline.com/doi/full/10.1080/15622975.2024.2346096 |journal=The World Journal of Biological Psychiatry |language=en |volume=25 |issue=5 |pages=291–303 |doi=10.1080/15622975.2024.2346096 |issn=1562-2975|url-access=subscription }}</ref> Researchers compared protein expression in serum samples of individuals with [[Depersonalization-derealization disorder|depersonalisation/derealization disorder]] (DPDR, DDD) and healthy controls, and found that many key proteins involved in maintaining [[homeostasis]] were present at altered levels. Decreased levels of [[C-reactive protein|C-reactive protein (CRP)]], [[Complement component 1q|complement C1q subcomponent subunit B]], and apolipoprotein A-IV, and increased levels of alpha-1-antichymotrypsin (SERPINA3) were observed in patients with DPDR. Furthermore, expressions of CRP and SERPINA3 were found to be linked with the ability to inhibit cognitive interference of DPDR.