Editing Desloratadine (section)

=== Pharmacogenomics ===
2% of [[Caucasian race|Caucasian]]s and 18% of people from African descent are desloratadine [[poor metabolizer]]s. In these people, the drug reaches threefold higher plasma concentrations at seven hours after intake, and it has a half-life of 89 hours (compared to a 27-hour half-life in normal metabolizers). Adverse effects were reported at similar rates in poor metabolizers, suggesting that it is not clinically relevant.<ref name="EPAR" /><ref name="Drugs.com" />