Editing Embryonic stem cell (section)

=== Tissue engineering ===
[[File:MESC EBs.jpg|thumb|Embryoid bodies 24 hours after formation.]]
In [[tissue engineering]], the use of stem cells are known to be of importance. In order to successfully engineer a tissue, the cells used must be able to perform specific biological functions such as secretion of cytokines, signaling molecules, interacting with neighboring cells, and producing an extracellular matrix in the correct organization. Stem cells demonstrates these specific biological functions along with being able to self-renew and differentiate into one or more types of specialized cells. Embryonic stem cells is one of the sources that are being considered for the use of tissue engineering.<ref>{{Cite journal|last1=Vats|first1=A|last2=Tolley|first2=N S|last3=Bishop|first3=A E|last4=Polak|first4=J M|date=2005-08-01|title=Embryonic Stem Cells and Tissue Engineering: Delivering Stem Cells to the Clinic|journal=Journal of the Royal Society of Medicine|language=en|volume=98|issue=8|pages=346–350|doi=10.1177/014107680509800804|pmid=16055897|pmc=1181832|issn=0141-0768|doi-access=free}}</ref>  The use of human embryonic stem cells have opened many new possibilities for tissue engineering, however, there are many hurdles that must be made before human embryonic stem cell can even be utilized. It is theorized that if embryonic stem cells can be altered to not evoke the immune response when implanted into the patient then this would be a revolutionary step in tissue engineering.<ref>{{Cite journal|date=2000-01-01|title=Cells for tissue engineering|url=https://www.sciencedirect.com/science/article/abs/pii/S0167779999013967|journal=Trends in Biotechnology|language=en|volume=18|issue=1|pages=17–19|doi=10.1016/S0167-7799(99)01396-7|issn=0167-7799|last1=Heath|first1=Carole A.|pmid=10631775|access-date=2021-04-13|archive-date=2021-04-13|archive-url=https://web.archive.org/web/20210413183507/https://www.sciencedirect.com/science/article/abs/pii/S0167779999013967|url-status=live|url-access=subscription}}</ref> Embryonic stem cells are not limited to tissue engineering.