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Endocrine disruptor
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=== Indoor air and household dust === With the increase in household products containing pollutants and the decrease in the quality of building ventilation, indoor air has become a significant source of pollutant exposure.<ref name=Weschler2009>{{cite journal | vauthors = Weschler CJ | year = 2009 | title = Changes in indoor pollutants since the 1950s | journal = Atmospheric Environment | volume = 43 | issue = 1 | pages = 153β169 | doi = 10.1016/j.atmosenv.2008.09.044 | bibcode = 2009AtmEn..43..153W }}</ref> Residents living in houses with wood floors treated in the 1960s with PCB-based wood finish have a much higher body burden than the general population.<ref name="Rudel_2008">{{cite journal |vauthors=Rudel RA, Seryak LM, Brody JG | title = PCB-containing wood floor finish is a likely source of elevated PCBs in residents' blood, household air and dust: a case study of exposure | journal = Environ Health | volume = 7 | issue = 1| page = 2 | year = 2008 | pmid = 18201376 | pmc = 2267460 | doi = 10.1186/1476-069X-7-2 | doi-access = free | bibcode = 2008EnvHe...7....2R }}</ref> A study of indoor house dust and dryer lint of 16 homes found high levels of all 22 different PBDE [[Congener (chemistry)|congeners]] tested for in all samples.<ref name="pmid15773463">{{cite journal |vauthors=Stapleton HM, Dodder NG, Offenberg JH, Schantz MM, Wise SA | title = Polybrominated diphenyl ethers in house dust and clothes dryer lint | journal = Environ. Sci. Technol. | volume = 39 | issue = 4 | pages = 925β31 |date=February 2005 | pmid = 15773463 | doi = 10.1021/es0486824 | bibcode = 2005EnST...39..925S }}</ref> Recent studies suggest that contaminated house dust, not food, may be the major source of PBDE in the body.<ref name="Anderson_2008">{{cite journal |vauthors=Anderson HA, Imm P, Knobeloch L, Turyk M, Mathew J, Buelow C, Persky V | title = Polybrominated diphenyl ethers (PBDE) in serum: findings from a US cohort of consumers of sport-caught fish | journal = Chemosphere | volume = 73 | issue = 2 | pages = 187β94 |date=September 2008 | pmid = 18599108 | doi = 10.1016/j.chemosphere.2008.05.052 | bibcode = 2008Chmsp..73..187A }}</ref><ref name="Morland_2005">{{cite journal |vauthors=Morland KB, Landrigan PJ, SjΓΆdin A, Gobeille AK, Jones RS, McGahee EE, Needham LL, Patterson DG | title = Body burdens of polybrominated diphenyl ethers among urban anglers | journal = Environmental Health Perspectives| volume = 113 | issue = 12 | pages = 1689β92 |date=December 2005 | pmid = 16330348 | pmc = 1314906 | doi = 10.1289/ehp.8138 | bibcode = 2005EnvHP.113.1689M }}</ref> One study estimated that ingestion of house dust accounts for up to 82% of humans' PBDE body burden.<ref name="Lorber_2008">{{cite journal | vauthors = Lorber M | title = Exposure of Americans to polybrominated diphenyl ethers | journal = J Expo Sci Environ Epidemiol | volume = 18 | issue = 1 | pages = 2β19 |date=January 2008 | pmid = 17426733 | doi = 10.1038/sj.jes.7500572 | doi-access = free | bibcode = 2008JESEE..18....2L }}</ref> It has been shown that contaminated house dust is a primary source of lead in young children's bodies.<ref name="pmid7354967">{{cite journal |vauthors=Charney E, Sayre J, Coulter M | title = Increased lead absorption in inner city children: where does the lead come from? | journal = Pediatrics | volume = 65 | issue = 2 | pages = 226β31 |date=February 1980 | pmid = 7354967 | doi = 10.1542/peds.65.2.226 }}</ref> It may be that babies and toddlers ingest more contaminated house dust than the adults they live with, and therefore have much higher levels of pollutants in their systems. [[File:Paraben-2D-skeletal.png|thumb|100px|The general chemical structure of a [[Paraben]]]]
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