Editing Gabapentin (section)

===Other===
Gabapentin is recommended as a first-line treatment of the acquired [[pendular nystagmus]], torsional nystagmus, and infantile nystagmus; however, it does not work in periodic alternating nystagmus.<ref>{{cite journal | vauthors = McLean RJ, Gottlob I | title = The pharmacological treatment of nystagmus: a review | journal = Expert Opinion on Pharmacotherapy | volume = 10 | issue = 11 | pages = 1805–1816 | date = August 2009 | pmid = 19601699 | doi = 10.1517/14656560902978446 | s2cid = 21477128 }}</ref><ref name="pmid22072056">{{cite journal | vauthors = Thurtell MJ, Leigh RJ | title = Treatment of nystagmus | journal = Current Treatment Options in Neurology | volume = 14 | issue = 1 | pages = 60–72 | date = February 2012 | pmid = 22072056 | doi = 10.1007/s11940-011-0154-5 | s2cid = 40370476 }}</ref><ref name="pmid22661344">{{cite journal | vauthors = Mehta AR, Kennard C | title = The pharmacological treatment of acquired nystagmus | journal = Practical Neurology | volume = 12 | issue = 3 | pages = 147–153 | date = June 2012 | pmid = 22661344 | doi = 10.1136/practneurol-2011-000181 | s2cid = 1950738 }}</ref>

Gabapentin decreases the frequency of [[hot flash]]es in both menopausal women and people with breast cancer. However, antidepressants have similar efficacy, and treatment with [[estrogen]] more effectively prevents hot flashes.<ref name="pmid31870736">{{cite journal | vauthors = Shan D, Zou L, Liu X, Shen Y, Cai Y, Zhang J | title = Efficacy and safety of gabapentin and pregabalin in patients with vasomotor symptoms: a systematic review and meta-analysis | journal = American Journal of Obstetrics and Gynecology | volume = 222 | issue = 6 | pages = 564–579.e12 | date = June 2020 | pmid = 31870736 | doi = 10.1016/j.ajog.2019.12.011 | s2cid = 209462426 }}</ref>

Gabapentin reduces [[spasticity]] in [[multiple sclerosis]] and is prescribed as one of the first-line options.<ref name="pmid27207462">{{cite journal | vauthors = Otero-Romero S, Sastre-Garriga J, Comi G, Hartung HP, Soelberg Sørensen P, Thompson AJ, Vermersch P, Gold R, Montalban X | title = Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper | journal = Multiple Sclerosis | volume = 22 | issue = 11 | pages = 1386–1396 | date = October 2016 | pmid = 27207462 | doi = 10.1177/1352458516643600 | s2cid = 25028259 | url = https://discovery.ucl.ac.uk/id/eprint/1496196/ }}</ref> It is an established treatment of [[restless legs syndrome]].<ref name="pmid29756335">{{cite journal | vauthors = Winkelmann J, Allen RP, Högl B, Inoue Y, Oertel W, Salminen AV, Winkelman JW, Trenkwalder C, Sampaio C | title = Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017)<sup>§</sup> | journal = Movement Disorders | volume = 33 | issue = 7 | pages = 1077–1091 | date = July 2018 | pmid = 29756335 | doi = 10.1002/mds.27260 | s2cid = 21669996 }}</ref> Gabapentin alleviates itching in kidney failure ([[uremic pruritus]])<ref>{{cite journal | vauthors = Berger TG, Steinhoff M | title = Pruritus and renal failure | journal = Seminars in Cutaneous Medicine and Surgery | volume = 30 | issue = 2 | pages = 99–100 | date = June 2011 | pmid = 21767770 | pmc = 3692272 | doi = 10.1016/j.sder.2011.04.005 | doi-broken-date = 1 November 2024 }}</ref><ref name="pmid33283264">{{cite journal | vauthors = Hercz D, Jiang SH, Webster AC | title = Interventions for itch in people with advanced chronic kidney disease | journal = The Cochrane Database of Systematic Reviews | volume = 2020 | issue = 12 | pages = CD011393 | date = December 2020 | pmid = 33283264 | pmc = 8094883 | doi = 10.1002/14651858.CD011393.pub2 }}</ref> and itching of other causes.<ref>{{cite journal | vauthors = Anand S | title = Gabapentin for pruritus in palliative care | journal = The American Journal of Hospice & Palliative Care | volume = 30 | issue = 2 | pages = 192–196 | date = March 2013 | pmid = 22556282 | doi = 10.1177/1049909112445464 | s2cid = 39737885 }}</ref> It may be an option in [[essential tremor|essential]] or [[orthostatic tremor]].<ref>{{cite journal | vauthors = Schneider SA, Deuschl G | title = The treatment of tremor | journal = Neurotherapeutics | volume = 11 | issue = 1 | pages = 128–138 | date = January 2014 | pmid = 24142589 | pmc = 3899476 | doi = 10.1007/s13311-013-0230-5 }}</ref><ref>{{cite journal | vauthors = Zesiewicz TA, Elble RJ, Louis ED, Gronseth GS, Ondo WG, Dewey RB, Okun MS, Sullivan KL, Weiner WJ | title = Evidence-based guideline update: treatment of essential tremor: report of the Quality Standards subcommittee of the American Academy of Neurology | journal = Neurology | volume = 77 | issue = 19 | pages = 1752–1755 | date = November 2011 | pmid = 22013182 | pmc = 3208950 | doi = 10.1212/WNL.0b013e318236f0fd }}</ref><ref>{{cite journal | vauthors = Sadeghi R, Ondo WG | title = Pharmacological management of essential tremor | journal = Drugs | volume = 70 | issue = 17 | pages = 2215–2228 | date = December 2010 | pmid = 21080739 | doi = 10.2165/11538180-000000000-00000 | s2cid = 10662268 }}</ref>

Gabapentin does not appear to provide benefit for [[bipolar disorder]],<ref name="Hong_2022" /><ref name="Berlin_2015"/><ref>{{cite journal | vauthors = Ng QX, Han MX, Teoh SE, Yaow CY, Lim YL, Chee KT | title = A Systematic Review of the Clinical Use of Gabapentin and Pregabalin in Bipolar Disorder | journal = Pharmaceuticals | volume = 14 | issue = 9 | pages = 834 | date = August 2021 | pmid = 34577534 | pmc = 8469561 | doi = 10.3390/ph14090834 | doi-access = free }}</ref> [[complex regional pain syndrome]],<ref>{{cite journal | vauthors = Tran DQ, Duong S, Bertini P, Finlayson RJ | title = Treatment of complex regional pain syndrome: a review of the evidence | journal = Canadian Journal of Anaesthesia | volume = 57 | issue = 2 | pages = 149–166 | date = February 2010 | pmid = 20054678 | doi = 10.1007/s12630-009-9237-0 | title-link = doi | doi-access = free }}</ref> post-surgical pain,<ref>{{cite journal | vauthors = Hamilton TW, Strickland LH, Pandit HG | title = A Meta-Analysis on the Use of Gabapentinoids for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty | journal = The Journal of Bone and Joint Surgery. American Volume | volume = 98 | issue = 16 | pages = 1340–1350 | date = August 2016 | pmid = 27535436 | doi = 10.2106/jbjs.15.01202 | url = https://ora.ox.ac.uk/objects/uuid:cbe29197-14a9-47dc-b961-2ad3e24fd1c0 | access-date = 22 August 2020 | url-status = dead | archive-url = https://web.archive.org/web/20200929012600/https://ora.ox.ac.uk/objects/uuid:cbe29197-14a9-47dc-b961-2ad3e24fd1c0 | archive-date = 29 September 2020 | url-access = subscription }}</ref> or [[tinnitus]],<ref>{{cite journal | vauthors = Aazh H, El Refaie A, Humphriss R | title = Gabapentin for tinnitus: a systematic review | journal = American Journal of Audiology | volume = 20 | issue = 2 | pages = 151–158 | date = December 2011 | pmid = 21940981 | doi = 10.1044/1059-0889(2011/10-0041) }}</ref> or prevent [[episodic migraine]] in adults.<ref>{{cite journal | vauthors = Linde M, Mulleners WM, Chronicle EP, McCrory DC | title = Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults | journal = The Cochrane Database of Systematic Reviews | volume = 2013 | issue = 6 | pages = CD010609 | date = June 2013 | pmid = 23797675 | pmc = 6599858 | doi = 10.1002/14651858.CD010609 }}</ref>