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Indigestion
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====Esophagitis==== [[Esophagitis]] is an inflammation of the esophagus, most commonly caused by gastroesophageal reflux disease ([[Gastroesophageal reflux disease|GERD]]).<ref name=":0" /> It is defined by the sensation of "[[heartburn]]" or a burning sensation in the chest as a result of inappropriate relaxation of the lower esophageal sphincter at the site where the esophagus connects to the stomach. It is often treated with proton pump inhibitors. If left untreated, the chronic damage to the esophageal tissues poses a risk of developing cancer.<ref name=":0" /> A meta-analysis showed risk factors for developing GERD included age equal to or greater than 50, smoking, the use of non-steroid anti-inflammatory medications, and obesity.<ref>{{Cite journal|last1=Eusebi|first1=Leonardo H.|last2=Ratnakumaran|first2=Raguprakash|last3=Yuan|first3=Yuhong|last4=Solaymani-Dodaran|first4=Masoud|last5=Bazzoli|first5=Franco|last6=Ford|first6=Alexander C.|date=March 2018|title=Global prevalence of, and risk factors for, gastro-oesophageal reflux symptoms: a meta-analysis|url=https://pubmed.ncbi.nlm.nih.gov/28232473|journal=Gut|volume=67|issue=3|pages=430β440|doi=10.1136/gutjnl-2016-313589|issn=1468-3288|pmid=28232473|s2cid=3496003}}</ref>
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