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Ischemia
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=== Kidney ischemia === [[Kidney ischemia]] is a loss of blood flow to the kidney cells. Several physical symptoms include shrinkage of one or both kidneys,<ref name=":0">{{cite journal|url=https://journals.lww.com/jhypertension/abstract/1997/15120/ischemic_renal_disease__an_emerging_cause_of.1.aspx|author-last1=Preston|author-first1=Richard A. |author-last2=Epstein|author-first2=Murray|title=Ischemic renal disease: an emerging cause of chronic renal failure and end-stage renal disease|journal=Journal of Hypertension|volume=15|number=12|pages=1365-1377|date=December 1997|access-date=2020-12-20}}</ref> [[renovascular hypertension]],<ref>{{Cite web|title=Renovascular hypertension: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/article/000204.htm|access-date=2020-12-20|website=medlineplus.gov|language=en}}</ref> [[Acute kidney injury|acute renal failure]],<ref name=":0" /> progressive azotemia,<ref name=":0" /> and acute [[pulmonary edema]].<ref name=":0" /> It is a disease with high mortality rate and high morbidity.<ref>{{Cite journal|last1=Sharfuddin|first1=Asif A.|last2=Molitoris|first2=Bruce A.|date=April 2011|title=Pathophysiology of ischemic acute kidney injury|url=https://www.nature.com/articles/nrneph.2011.16|journal=Nature Reviews Nephrology|language=en|volume=7|issue=4|pages=189β200|doi=10.1038/nrneph.2011.16|pmid=21364518|s2cid=32234965|issn=1759-507X|url-access=subscription}}</ref> Failure to treat could cause [[chronic kidney disease]]<ref>{{Cite journal|last1=Zuk|first1=Anna|last2=Bonventre|first2=Joseph V.|date=2016-01-14|title=Acute Kidney Injury|journal=Annual Review of Medicine|volume=67|issue=1|pages=293β307|doi=10.1146/annurev-med-050214-013407|issn=0066-4219|pmc=4845743|pmid=26768243}}</ref> and a need for renal surgery.<ref>{{Cite journal|last1=Munshi|first1=Raj|last2=Hsu|first2=Christine|last3=Himmelfarb|first3=Jonathan|date=2011-02-02|title=Advances in understanding ischemic acute kidney injury|url= |journal=BMC Medicine|volume=9|issue=1|pages=11|doi=10.1186/1741-7015-9-11|issn=1741-7015|pmc=3038966|pmid=21288330 |doi-access=free }}</ref>
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