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LSD
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===Psychological=== The primary immediate psychological effects of LSD are [[visual hallucination|visual pseudo-hallucination]]s and altered thought, often referred to as "trips". These sensory alterations are considered pseudohallucinations because the subject does not perceive the patterns seen as being located in three-dimensional space outside the body.<ref>{{cite journal | vauthors = El-Mallakh RS, Walker KL | title = Hallucinations, psuedohallucinations, and parahallucinations | journal = Psychiatry | volume = 73 | issue = 1 | pages = 34β42 | date = 2010 | pmid = 20235616 | doi = 10.1521/psyc.2010.73.1.34 }}</ref> LSD is not considered addictive. These effects typically begin within 20β30 minutes of oral ingestion, peak three to four hours after ingestion, and can last up to 20 hours, particularly with higher doses. An "[[afterglow (drug culture)|afterglow]]" effect, characterized by an improved mood or perceived mental state, may persist for days or weeks following ingestion.<ref>{{cite journal |vauthors=MajiΔ T, Schmidt TT, Gallinat J |title=Peak experiences and the afterglow phenomenon: when and how do therapeutic effects of hallucinogens depend on psychedelic experiences? |journal=Journal of Psychopharmacology |volume=29 |issue=3 |pages=241β253 |date=March 2015 |pmid=25670401 |doi=10.1177/0269881114568040 |s2cid=16483172}}</ref> Positive experiences, or "good trips", are described as intensely pleasurable and can include feelings of joy, euphoria, an increased appreciation for life, decreased anxiety, a sense of spiritual enlightenment, and a feeling of interconnectedness with the universe.<ref name="erowid-faq">{{cite web |work=[[Erowid]] |vauthors=Honig D |title=Frequently Asked Questions |url=http://www.erowid.org/chemicals/lsd/lsd_faq.shtml |archive-url=https://web.archive.org/web/20160212232436/https://www.erowid.org/chemicals/lsd/lsd_faq.shtml |archive-date=12 February 2016}}</ref><ref name="PMID6054248">{{cite journal |vauthors=McGlothlin W, Cohen S, McGlothlin MS |title=Long lasting effects of LSD on normals |journal=Archives of General Psychiatry |volume=17 |issue=5 |pages=521β532 |date=November 1967 |pmid=6054248 |doi=10.1001/archpsyc.1967.01730290009002| url=http://www.maps.org/w3pb/new/1967/1967_mcglothlin_4655_1.pdf |archive-date=April 30, 2011 |archive-url=https://web.archive.org/web/20110430020912/http://www.maps.org/w3pb/new/1967/1967_mcglothlin_4655_1.pdf}}</ref> Negative experiences, commonly known as "[[bad trip]]s", can induce feelings of fear, agitation, anxiety, panic, and paranoia.<ref name="PassieHalpernStrichtenoth2008" /><ref name="kopra_adverse">{{cite journal | vauthors = Kopra EI, Ferris JA, Rucker JJ, McClure B, Young AH, Copeland CS, Winstock AR | title = Adverse experiences resulting in emergency medical treatment seeking following the use of lysergic acid diethylamide (LSD) | journal = Journal of Psychopharmacology | volume = 36 | issue = 8 | pages = 956β964 | date = August 2022 | pmid = 35672900 | pmc = 9353972 | doi = 10.1177/02698811221099650 }}</ref> While the occurrence of a bad trip is unpredictable, factors such as mood, surroundings, sleep, hydration, and social setting, collectively referred to as "[[set and setting]]", can influence the risk and are considered important in minimizing the likelihood of a negative experience.<ref name=MedlinePlus>{{citation |title=Substance use β LSD |vauthors=Rogge T |date=21 May 2014 |access-date=14 July 2016 |publisher=MedlinePlus, U.S. National Library of Medicine |url=https://medlineplus.gov/ency/patientinstructions/000795.htm |url-status=live|archive-url=https://web.archive.org/web/20160728004220/https://medlineplus.gov/ency/patientinstructions/000795.htm|archive-date=July 28, 2016}}</ref><ref name=CESAR>{{citation|title=LSD |author=CESAR |publisher=Center for Substance Abuse Research, University of Maryland |date=29 October 2013 |access-date=14 July 2016 |url=http://www.cesar.umd.edu/cesar/drugs/lsd.asp |archive-url=https://web.archive.org/web/20160715071823/http://www.cesar.umd.edu/cesar/drugs/lsd.asp |archive-date=July 15, 2016}}</ref>
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