Editing Liver function tests (section)

===Gamma-glutamyltransferase (GGT)===
{| class="wikitable" align="right"
| Reference range
|-
| 9 to 85 IU/L<ref name="Shivaraj 2009"/>
|}
{{Main|Gamma-glutamyltransferase}}
GGT is a microsomal enzyme found in hepatocytes, biliary epithelial cells, renal tubules, pancreas, and intestines. It helps in [[glutathione]] metabolism by transporting peptides across the cell membrane. Much like ALP, GGT measurements are usually elevated if cholestasis is present.<ref name=":0" /> In acute viral hepatitis, the GGT levels can peak at 2nd and 3rd week of illness, and remained elevated at 6 weeks of illness. GGT is also elevated in 30% of the hepatitis C patients. GGT can increase by 10 times in alcoholism. GGT can increase by 2 to 3 times in 50% of the patients with non-alcoholic liver disease. When GGT levels is elevated, the [[triglyceride]] level is elevated also. With insulin treatment, the GGT level can reduce. Other causes of elevated GGT are: diabetes mellitus, [[acute pancreatitis]], myocardial infarction, [[anorexia nervosa]], [[Guillain–Barré syndrome]], hyperthyroidism, obesity and [[myotonic dystrophy]].<ref name="Shivaraj 2009"/>

In pregnancy conditions GGT activity is reduced in 2nd and 3rd trimesters. In hyperemesis gravidarum, GGT level value can reach 45 IU/L, 17 IU/L in pre-eclampsia, and 35 IU/L in HELPP syndrome.<ref name="Shivaraj 2009"/>