Editing Lymph (section)

==Clinical significance==
{{expand section|date=March 2018}}
[[Histology|Histopathological examination]] of the lymph system is used as a screening tool for [[immune system]] analysis in conjunction with pathological changes in other [[organ (anatomy)|organ systems]] and [[clinical pathology]] to assess disease status.<ref name="Elmore11">{{cite journal | last=Elmore | first=Susan A. | title=Enhanced histopathology of the immune system | journal=Toxicologic Pathology | volume=40 | issue=2 | date=16 November 2011 | issn=0192-6233 | doi=10.1177/0192623311427571 | pages=148–156|pmid=22089843|pmc=3465566}}</ref> Although histological assessment of the lymph system does not directly measure immune function, it can be combined with identification of chemical [[biomarker]]s to determine underlying changes in the diseased immune system.<ref name="Elmore18">{{cite book | last=Elmore | first=Susan A. | title=Immunotoxicity Testing | volume=1803 | chapter=Enhanced Histopathology Evaluation of Lymphoid Organs | series=Methods in Molecular Biology | year=2018 | isbn=978-1-4939-8548-7 | issn=1064-3745 | doi=10.1007/978-1-4939-8549-4_10 | pages=147–168|pmid=29882138}}</ref>