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Malignant transformation
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===Viruses=== In 2002 the [[World Health Organization]]s [[International Agency for Research on Cancer]]<ref name=Parkin06>{{Cite journal|doi= 10.1002/ijc.21731 |title= The global health burden of infection-associated cancers in the year 2002 |year= 2006 |last1= Parkin |first1= Donald Maxwell |journal= International Journal of Cancer |volume= 118 |pmid= 16404738 |issue= 12|pages= 3030β44|doi-access= free }}</ref> estimated that 11.9% of human cancers are caused by one of seven viruses (see [[Oncovirus#Overview table|Oncovirus overview table]]). These are [[Epstein-Barr virus]] (EBV or HHV4); [[Kaposi's sarcoma-associated herpesvirus]] (KSHV or HHV8); [[Hepatitis B]] and [[Hepatitis C]] viruses (HBV and HCV); [[Human T-lymphotrophic virus]] 1 (HTLV-1); [[Merkel cell polyomavirus]] (MCPyV); and a group of alpha [[Human papillomaviruses]] (HPVs).<ref name="pmid28104704">{{cite journal |vauthors=McBride AA |title=Perspective: The Promise of Proteomics in the Study of Oncogenic Viruses |journal=Mol. Cell. Proteomics |volume= 16|issue= 4 suppl 1|pages= S65βS74|year=2017 |pmid=28104704 |doi=10.1074/mcp.O116.065201 |doi-access=free |pmc=5393395}}</ref>
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