Editing Microtome (section)

===Cryomicrotome===
{{See also|Frozen section procedure}}
[[File:Cryostat microtome.jpg|thumb|left|A cryomicrotome]]

For the cutting of frozen samples, many rotary microtomes can be adapted to cut in a liquid-nitrogen chamber, in a so-called cryomicrotome setup. The reduced temperature allows the hardness of the sample to be increased, such as by undergoing a glass transition, which allows the preparation of semi-thin samples.<ref name="Lang" /> However the sample temperature and the knife temperature must be controlled in order to optimise the resultant sample thickness.