Editing Mood stabilizer (section)

===Combination therapy===
In routine practice, monotherapy is often not sufficiently effective for acute and/or maintenance therapy and thus most patients are given [[combination therapy|combination therapies]].<ref name=Geoffroy-2012/> Combination therapy (atypical antipsychotic with lithium or valproate) shows better efficacy over monotherapy in the manic phase in terms of efficacy and prevention of relapse.<ref name=Geoffroy-2012/> However, side effects are more frequent and discontinuation rates due to adverse events are higher with combination therapy than with monotherapy.<ref name=Geoffroy-2012>{{Cite journal | last1 = Geoffroy | first1 = P. A. | last2 = Etain | first2 = B. | last3 = Henry | first3 = C. | last4 = Bellivier | first4 = F. | title = Combination Therapy for Manic Phases: A Critical Review of a Common Practice | doi = 10.1111/cns.12017 | journal = CNS Neuroscience & Therapeutics | volume = 18 | issue = 12 | pages = 957–964 | year = 2012 | pmid = 23095277 | pmc = 6493634| url = http://www.hal.inserm.fr/inserm-00786653/document }}</ref>