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Nasal polyp
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===Histology=== [[File:Nasal polyp 25x H+E (1).tif|thumb|Histology of nasal polyp, magnification 25x ([[H&E stain]])]] On histologic examination, nasal polyps consist of hyperplastic edematous (excess fluid) [[connective tissue]] with some [[seromucous gland]]s and cells representing inflammation (mostly [[neutrophil]]s and [[eosinophil]]s). Polyps have virtually no neurons. Therefore, the tissue that makes up the polyp does not have any tissue sensation and the polyp itself will not be painful.<ref name="Mid2014" /> In early stages, the surface of the nasal polyp is covered by normal respiratory epithelium, but later it undergoes [[metaplasia|metaplastic]] change to squamous type epithelium with the constant irritation and inflammation. The submucosa shows large intercellular spaces filled with serous fluid.<ref>{{Cite book |last=Michaels |first=Leslie |url=https://books.google.com/books?id=Zm3jBwAAQBAJ&pg=PA168 |title=Ear, Nose and Throat Histopathology |date=2012-12-06 |publisher=Springer Science & Business Media |isbn=9781447133322 |page=168 |language=en}}</ref>
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