Editing Neocortex (section)

==Clinical significance==
Lesions that develop in [[neurodegenerative disorders]], such as [[Alzheimer's disease]], interrupt the transfer of information from the sensory neocortex to the prefrontal neocortex. This disruption of sensory information contributes to the progressive symptoms seen in neurodegenerative disorders such as changes in personality, decline in cognitive abilities, and [[dementia]].<ref name="Pathological changes in the parahippocampal region in select non-Alzheimer's dementias">{{cite book|vauthors=Braak H, Del-Tredici K, Bohl J, Bratzke H, Braak E|title=Annals of the New York academy of sciences, Vol. 911.|date=2000|publisher=New York, NY, US: New York Academy of Sciences|isbn=1-57331-263-0}}</ref> Damage to the neocortex of the anterolateral temporal lobe results in [[semantic dementia]], which is the loss of memory of factual information ([[semantic memories]]). These symptoms can also be replicated by [[transcranial magnetic stimulation]] of this area. If damage is sustained to this area, patients do not develop [[anterograde amnesia]] and are able to recall [[Episodic memory|episodic information]].<ref>{{cite book|last=Carlson|first=Neil | name-list-style = vanc |title=Physiology of Behavior|date=2013|publisher=Pearson|isbn=978-0-205-23948-1}}</ref>